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“I have been transformed in my body from how I was last year – looking at pictures from the time I was worn and tired, but this has made such a difference.

“Before I was very weak in my legs and could not walk far. I had horrendous night sweats, often had to sleep during the day, a miss-beat in my heart and cold feet. All that has gone.”

David said they saw the difference when they walked on the Caspian Sea beach at Varna after she had recovered from the procedure – the day before Jayne had managed less than 20 minutes; afterwards it was nearer to an hour and-a-half.

“It has given Jayne a new lease of life, so that she is capable of doing normal things again,” he said