This Is MS Multiple Sclerosis Community: Knowledge & Support

Dr. Zamboni has applied for a patent on a valvulotomy device:


http://www.wipo.int/pctdb/en/wo.jsp?IA=IB2010053355

Is he having success with valvulotomy as compared to ballooning? My thought is that valvulotomy has a greater risk of clotting, particularly in the low-flow, posture-dependent jugulars.

This is the picture of the device.
I do not think the risk of clotting is significant.

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Everybody here brings happiness, somebody by coming,others by leaving.  PPMS since 2000<br />

Dr. Sinan told us that he uses this way,

my sister had (Als) .. she tried to travel for re-catheter and Make (valvulotomy) vs ballooning, but unfortunately .. she could not travel because of the deterioration of her health .
she died two weeks ago ..

Sara-sama, condolences for your loss. I am sorry to hear of it.

Nunzio, thank you for the diagram, where did you find it? It's helpful.

If cutting balloons increase the risk of clotting, which I have heard here to be true, then a valvulotome would also increase the risk of clotting, as it is a bigger intervention than a cutting balloon?

wow! this thing is amazing... I wonder if something similar is being considered for clearing blockages. I'm picturing gentle tunneling tools and if that 'catch it' basket works it would certainly decrease the risk of clots escaping.
Science is awesome.

The basket should work.
IR are used to Inf Vena cava filters that look like umbrellas and are used to catch blood clot from the legs and prevent pulmonary embolism.

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Everybody here brings happiness, somebody by coming,others by leaving.  PPMS since 2000<br />

My guess is that the cleaner the cut the less chance of clotting.
Cutting balloons create more of an indentation and tear than a cut and that might be the reason for the higher risk of clotting.

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Everybody here brings happiness, somebody by coming,others by leaving.  PPMS since 2000<br />

The title of this thread is misleading. It is not Valvulotomy verses Ballooning but Valvulotomy or Ballooning. Solving valve issues by valvulotomy may be a future development. I am not familiar with the approval processes for new surgical equipment. If it is like approval of an internal medical device it could take years before this device could be available for use on our faulty valves.

Markw

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Mark Walker - Oxfordshire, England. Registered Pharmacist (UK). 10 years of study around MS.
Mark's CCSVI Report 7-Mar-11:
http://www.telegraph.co.uk/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html

I'm so sorry for your loss. My thoughts and prayers are with you and your family.

Thanks Cece & Trish

Condolences for your loss.
Do you know anything about dr Sinan's technique? Does he use the valvulotomy or the cutting ballon?

Thanks Liberation
I do not know waht his technique exactly ..
I understood that he cut the valve to keep the vein open ..

I am pondering the differences between vs and 'or' now! Versus is if it is a head-to-head challenge, 'or' is if it is merely one or the other?

For myself I prefer Ballooning to valvulotomy, at least until there is more information on how the blood vessel tolerates valvulotomy, as the latter does seem more invasive. But I have seen some images -- I am thinking of one that Dr. Cumming posted in the doctors' thread -- where a stenosis just elastic recoils right back. If that is a valvular stenosis, which they nearly all are, a valvulotome could be an option as a secondary choice in a situation where the first choice, ballooning, has failed. This would also push stents further down the list of options, which is good, because stents are not good....(imo)

MarkW, I don't know if there is an FDA approved valvulotome here in the US or over in UK? They do exist, as was said already that Dr. Sinan has used one. I do not know if he frequently uses it. The one in Dr. Zamboni's patent is more perfectly designed for CCSVI usage, especially with that little basket - will wonders never cease.

If as Dr. SClafani has recently suggested, annular stenoses are more difficult to treat with ballooning than fused leaflets, perhaps when facing an annular stenosis, an IR might first balloon it (pop) and then follow with a valvulotome? That would make elastic recoil stenosis less likely! But thrombosis more likely. I think.

sara-sama

sorry for your loss.

our neighbor/friend died in january bfrom als. horrible disease.

Thanks (IHateMS)

yes , it is horrible disease.