Current thinking in MS

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Current thinking in MS

Postby Shannon » Wed Mar 23, 2011 6:14 am

This is probably nothing new, but just thought I would share it since it is a new article. Of course, we now also know that CCSVI is a major pre-existing condition.

Mt Sinai J Med. 2011 Mar;78(2):221-30. doi: 10.1002/msj.20240.

Environmental factors in multiple sclerosis: epstein-barr virus, vitamin d, and cigarette smoking.
Wingerchuk DM.

Department of Neurology, Mayo Clinic, Scottsdale, AZ. wingerchuk.dean@mayo.edu.

Abstract
Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system. Although its cause is not known, genetic and environmental factors both influence susceptibility to the disease. From the large array of environmental risk factors that have been examined over the past century, infection with Epstein-Barr virus, ultraviolet light exposure/vitamin D status, and cigarette smoking stand out because of the strength of supporting evidence. Epstein-Barr virus infection early in life appears to be necessary permissive step for disease development and probably acts in adolescence and early adulthood. Vitamin D-related mechanisms and cigarette smoking probably modify baseline disease risk and could plausibly do so at several stages of life; smoking appears to negatively affect disease course. This review summarizes current evidence for these 3 putative multiple sclerosis risk factors and early attempts to develop risk models and examine gene-environment interactions for this complex disease. Mt Sinai J Med 78:221-230, 2011 © 2011 Mount Sinai School of Medicine.

© 2011 Mount Sinai School of Medicine.
PMID: 21425266 [PubMed - in process]
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Postby 1eye » Wed Mar 23, 2011 7:03 am

Is it because it is a pre-existing condition that Ontario hospitalization insurance won't recognize it? I certainly hope the feds will, at least on my tax return. I also know that the insurance company in Canada won't recognize it, even as a medical expense. Do they in the US? The idea of a pre-existing condition was I thought deprecated in the US by Mr. Obama.
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Postby PCakes » Wed Mar 23, 2011 7:37 am

Environmental factors in multiple sclerosis: epstein-barr virus, vitamin d, and cigarette smoking.


With close to 100% of the population's exposure to smoking or secondhand smoke, 95% exposed to the EB virus by adulthood and the current epidemic of vitamin D deficiency.. bit like saying if you have eyes and ears? I think there might be a very important piece of this puzzle missing. ;)
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Re: Current thinking in MS

Postby 1eye » Thu Sep 22, 2011 12:20 pm

With close to 100% of the population's exposure to smoking or secondhand smoke, 95% exposed to the EB virus by adulthood and the current epidemic of vitamin D deficiency
How about that both cause coughing, EBV violently. and smoking chronically, and that coughing causes reflux? Maybe they both cause damage to jugulars/valves/already-congenitally-diseased veins? Doesn't smoking constrict vessels? What are its chronic effects on circulation/endothelium/smooth-muscle-tone?
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Re: Current thinking in MS

Postby fee001 » Thu Sep 22, 2011 1:33 pm

Hi!


It is a total coinsidence that I have just been writing on general about Glandular fever EBV.

Thats just so weird

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