Researchers have recently discovered a possible association between MS and CCSVI. CCSVI occurs when the flow of blood in the veins of the chest and neck is compromised. This causes less efficient draining of blood from the brain. It is proposed that insufficient venous blood flow, in turn, promotes development of brain dysfunction, especially in MS.
What are the symptoms or consequences of CCSVI?
Proposed consequences of CCSVI syndrome include intracranial hypoxia, delayed perfusion, reduced drainage of catabolites, increased transmural pressure, and iron deposits around the cerebral veins. Iron deposition as a cause of MS received support when a relation between venous pressure and iron depositions in MS patients was found in a neuroimaging study. CCSVI itself, regardless of MS presence, is known to cause mind impairment.