check your PM'sleetz wrote:donchadh...you can tell us you know...just what u take or pm us and let us know that has nothing to do with Karma? it is just what works for you...
Donnchadh
I understand, of course, that hemolobin would use iron as a main constituent, and that after giving blood you would need to reconstitute your red blood cells, i.e. hemoglobin. It just would not be made using free iron deposits in the brain.Donnchadh wrote:By donating a pint of whole blood, the body is forced to draw down iron stores to start the process of creating replacement red blood cells. At the "heart" of hemoglobin is iron. That's why red blood cells can transport oxygen to the body; iron captures and releases it.fogdweller wrote:I am not sure why whole blood donation might help. Supplements might make sense, some chelation going on. What supplements? I promise not to hurt myself.Donnchadh wrote:Long before I ever heard of CCSVI, I found out that donating whole blood really helped with fatigue-why I don't know. Just that I felt better.
Same with many other supplements; a wide range of results.
Donnchadh
Personally, I suspect a complex combination. The breakdown of the bloodbrain barrier may lead to hemosiderin being released into the brain, which would be prevented if the BBB was intact. Is this different than the iron that is detected by Zamboni in the brain? Iron deposits could interfere with the complex interactions goining on in the brain and led to a number of problems that would sound like MS symptoms.Cece wrote:In Zamboni's theory, it's not free iron deposits in the brain that is the main culprit, is it? It is red blood cells that get through the leaky endothelium. These break down into hemosiderin.
I am personally partial to what was presented at ISNVD on the hypoxia of axons early in the course of MS, thus making direct hypoxia a means of damaging the brain, not the iron deposits. Although maybe the iron deposits lead to the lesions, while the direct hypoxia leads to the NAWM with damaged axons underneath.
You wouldn't be eligible at the blood bank I go to because of the "MS" autoimmune drugs you took, however your doctor can make an order for a blood draw. You would have to pay for it.zanne10000 wrote:Blossom, I love that someone finally mentioned hemochromatosis! I had never heard of it until I had to come off of Avonex after only 3 months. My liver enzymes were 10x normal and I was sent to a GI specialist. He tested me for everything, including this. Finally, after about 6 weeks had passed since I had stopped Avonex, my levels finally started to drop and he concluded that he could safely say it was the drug that caused such chaos in my liver. I was so relieved because he was about to order a liver biopsy!
I didn't test positive for hemochromatosis, but you can bet I did a lot of reading on it when I was waiting for my results.
Donnchadh, I love your theory. I always tend to be a bit high on iron, but interestingly, in my Haacke report, I didn't have any iron deposition in my brain. So... where does this leave me? I'm not sure, but this was a very interesting thread for me. Glad everyone is on top of it! Don't know if I could give blood anymore, since I've taken Copaxone, Avonex and Tysabri, but I used to give blood regularly (before I was diagnosed with MS-- maybe that's one way to ward off the onset?!).