Intra-luminal structural abnormalities:
Extra-luminal structural abnormalities:
prairie wrote:The video segements from the Buffalo Patient Education program on May 7,2011 are also now on YouTube.
Also needed is a study of Do-Not-Resuscitate cases to see if their status, like Mrs. Farrel's, improves.
Cece wrote:Also needed is a study of Do-Not-Resuscitate cases to see if their status, like Mrs. Farrel's, improves.
Dr. Sclafani said, back in January, that he was one of the few IRs willing to treat patients in the upper levels of EDSS.
I think a study of DNR cases is very unlikely. The ethics get murky and there is a greater risk of patient death during the study due to the MS. Better to provide compassionate care to all upper level MS patients, even if they are necessarily excluded from studies.
I agree about studying CCSVI treatment in progressive cases. It takes away the question about the natural course of the disease or potential remissions. Progressive is however very slow, I would not want to see a control group going untreated for a very long time just to show the effects in the treated group.
Trial design is as complicated as it was last year! Maybe more so, now that we know how varied the doctors are in their techniques.
Of course, there could be no placebo group! I just think it is unethical *not* to provide it as an option for compassionate care, and that it would be unthinkable to waste the treatment by not studying it.
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