This Is MS Multiple Sclerosis Community: Knowledge & Support

this is a quote from wikipedia, apologies that it is not a better source:


http://en.wikipedia.org/wiki/Oligoclonal_band

If CCSVI treatment is successful, will the oligoclonal bands disappear, as they tend to do when a person recovers from neurological disease? People don't recover from MS...but maybe they do, now. Wouldn't this be powerful evidence, if indeed these go away.

we've discussed this before, and it's a great point, Cece. The problem is, who wants to have a voluntary lumbar puncture to check for o-bands? Jeff's already said, thanks, but no thanks....one was enough for him.

If there are any volunteers who have had CCSVI angioplasty, had bands in spinal fluid before, and would want to coordinate this new test with their neuro, I wish them God-speed.

cheer

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Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
dual stents placed 5/09
CCSVI in MS

Maybe some people would be willing to do it in exchange for a free angioplasty. A clinical trial measuring OBs probably would recruit enough people to reach a conclusion.

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You can get a worldwide list of available sites for CCSVI at http://www.ccsviclinic.info

Been dying to know this from the git go. My thoughts exactly too, if those bands are gone, after I was told they only needed to be tested for once..hmmm. I mean, the LP wasn't "fun", but the very thought of vanishing oligoclonal bands is almost too much to resist haha. I had another LP just one year prior to hearing about CCSVI, but it was unrelated to the MS stuff. My neuro was miffed I didn't have some of the fluid saved so he could look at it, like how was I sposed to know that?

I'll ask him when I do a visit with him maybe this month. Finally got insurance back.
M

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RRMS Dx'd 2007, first episode 2004. Bilateral stent placement, 3 on left, 1 stent on right, at Stanford August 2009. Watch my operation video: http://www.youtube.com/watch?v=cwc6QlLVtko, Virtually symptom free since, no relap

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"Therefore we do not lose heart. Though outwardly we are wasting away, yet inwardly we are being renewed day by day." 2 Corinthians 4:16

I've often thought something similar from day 1.

My last neuro doesn't use o-bands as a marker for MS since they aren't present in 100% of us. But he does analyze disease activity by culturing T and B cells in the CSF extracted thru an LP. He periodically made treatment decisions by doing an LP and making comparisions, generally every 6 months. They were done in his office, sitting up but hunched over, and were no big deal. I only had a headache once and had a least 10 of them.

I believe a baseline cell measurement is important and periodic follow-up ones would answer alot of questions.

The neuros do not feel they've found a biomarker for MS, and therefore, wouldn't agree on the methodology.

In fact the presence and absence of OBs (Oligoclonal bands) looks like a very important difference. I don't understand why MS is classified according to the clinical course (RRMS, SPMS, PPMS) and biochemical differences as the presence of OBs are ignored.

Cases with and without OBs should be studied separately.

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You can get a worldwide list of available sites for CCSVI at http://www.ccsviclinic.info