VIAGRA COULD REDUCE MS SYMPTOMS

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Postby Cece » Thu Jun 09, 2011 4:38 pm

www.reuters.com/article/2008/01/08/us-l ... 5220080108

Low dose daily Cialis. (Otherwise it's 8 pills a month, with most prescription plans.)

Daily would be more consistent, for sustained blood flow to the brain.

:)

If your brain is, ahem, for more than four hours, please seek medical attention.
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Postby foreignlesion » Mon Jun 13, 2011 3:49 pm

I posted this a while back about a study that shows Viagra increases the permeability of the Blood Brain Barrier, which I don't think would be too advantageous to PwMS.

http://www.thisisms.com/ftopict-12210-viagra.html
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Postby Shannon » Mon Jun 13, 2011 5:31 pm

Thank you for re-posting that. I guess that would probably be a bad thing for us, but then again if the BBB is already being breached, then maybe wouldn't matter much. :?:
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Postby 1eye » Tue Jun 14, 2011 4:44 am

There are apparently others. Levitra is one good one.
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Postby dc10 » Fri Jul 15, 2011 2:46 pm

Has anyone given low dose Cialis a try?

if so what changes did you notice?
Last edited by dc10 on Sat Jul 16, 2011 10:22 am, edited 1 time in total.
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Postby civickiller » Fri Jul 15, 2011 2:53 pm

what about Male Enhancement Drugs, like Extenzes?

viagra should work on women right for increased blood flow ?
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Postby dc10 » Sat Jul 23, 2011 12:31 pm

bump


anyone tried low dose viagra for post CCSVI ballooning?
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Postby Ernst » Sun Jul 24, 2011 12:26 pm

.. and what about L-argine? It is quite commonly used by athletes and men with erection problems use it. It helps with Nitric oxide production in veins and there are many studies about it.. mostly with lab-rats, like this:

http://www.ncbi.nlm.nih.gov/pubmed/12614590

"L-arginine and free radical scavengers increase cerebral blood flow and brain tissue nitric oxide concentrations after controlled cortical impact injury in rats"
--> These studies support the theory that L-arginine administration improves post-traumatic cerebral blood flow by increasing NO production

PS. and some info in livestron.com "L-Arginine Effects on the Brain"

http://www.livestrong.com/article/379137-l-arginine-effects-on-the-brain/
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Postby jay123 » Sun Aug 14, 2011 7:01 am

I have definitely noticed a difference in balance and mobility 'the day after' V. I am going to request the daily does of cialis from my doc this week and do my own study.
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Postby dania » Sun Aug 14, 2011 7:26 am

jay123 wrote:I have definitely noticed a difference in balance and mobility 'the day after' V. I am going to request the daily does of cialis from my doc this week and do my own study.

Lucky you! Hope it continues to work for you. Anything that can help us!
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VIAGRA MAY BE NEUROPROTECTIVE & REDUCE MS SYMPTOMS

Postby MarkW » Tue Sep 13, 2011 8:03 am

VIAGRA MAY BE NEUROPROTECTIVE & REDUCE MS SYMPTOMS
Seemed to be good for mice with EAE who were given it for 8 days. Details in press release from UAB:
http://www.uab.es/PDF/PDF_1306480140723_en.pdf
No info on dose. If action is neuroprotective may work in females. Applies to similar (PDE5) drugs.

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Re: VIAGRA COULD REDUCE MS SYMPTOMS

Postby dc10 » Sun Sep 25, 2011 12:49 pm

has any other men tried Cialis on a daily casis?

what daily dose? what results did you notice?

i am going to start a 2 week trial of cialis but not sure of what dose?
also what risks am i taking by using a daily dose of cialis for 2 weeks?

thanks
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Re: VIAGRA COULD REDUCE MS SYMPTOMS

Postby questor » Sun Sep 25, 2011 5:18 pm

dc10 wrote:...also what risks am i taking by using a daily dose of cialis for 2 weeks?
thanks

Two weeks of non-stop headache seems like a heavy price to pay for whatever benefit you may achieve. But, good luck.

I suppose not everyone gets a headache from cialis, but many do. I don't know if this side effect is dose-dependent, but I'd read up on potential side-effects of cialis if I were you.

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Re:

Postby Jugular » Wed Oct 19, 2011 3:05 pm

Ernst wrote:.. and what about L-argine? It is quite commonly used by athletes and men with erection problems use it. It helps with Nitric oxide production in veins and there are many studies about it.. mostly with lab-rats, like this:

http://www.ncbi.nlm.nih.gov/pubmed/12614590

"L-arginine and free radical scavengers increase cerebral blood flow and brain tissue nitric oxide concentrations after controlled cortical impact injury in rats"
--> These studies support the theory that L-arginine administration improves post-traumatic cerebral blood flow by increasing NO production

PS. and some info in livestron.com "L-Arginine Effects on the Brain"

http://www.livestrong.com/article/379137-l-arginine-effects-on-the-brain/

I've been looking into L-Arginine as a potential supplement. What I find worisome is that Viagra and L-Arginine increase nitric oxide - though through different mechanisms.
NO has a role in several features of the disease, including disruption of the blood—brain barrier, oligodendrocyte injury and demyelination, axonal degeneration, and that it contributes to the loss of function by impairment of axonal conduction


http://www.thelancet.com/journals/laneu ... 74-4422(02)00102-3/abstract

And, from the same article:

However, despite these considerations, the net effect of NO production in MS is not necessarily deleterious because it also has several beneficial immunomodulatory effects. These dual effects may help to explain why iNOS inhibition has not provided reliable and encouraging results in animal models of MS, but alternative approaches based on the inhibition of superoxide production, partial sodium-channel blockade, or the replacement of lost immunomodulatory function, may prove beneficial.
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Re: VIAGRA COULD REDUCE MS SYMPTOMS

Postby PointsNorth » Wed Oct 19, 2011 4:31 pm

I notice that some (human) users of l'arginine report reduction in fatigue.
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