1eye wrote:Sounds to me like the fatigue is directly attributable to low oxygenation. I wonder how temperature figures into all this? Maybe cooler thicker blood goes through slower and the brain can get more oxygen out of it during the slower transit?
I would have thought heat would make the blood thinner and move quicker, improving the situation. Do we need more oxygen when hot?
All these heating and cooling relationships in the body fascinate me 1eye, as this is part of my trade, namely heat transfer to and from various units and pieces of machinery, from air conditioning to cooling towers.
The body, not quite as simple, there's so much to it beyond just "blood carrying heat away from the body", as you intimate, oxygenation etc. etc.
I will echo others like Cece, relapse or remit all you like, even though I was not in a verifiable exacerbation, the infernal fatigue would NOT remit no matter what I did or how I did it, my guess in relation to your comments, is that our oxygen starved CCSVI plagued systems, already in a deprived state, are (in a heated/overheated situation), now working doubletime, attempting to increase flow to the head which the body is always keen to protect first, but it can't get through anyways, during increased cardiac output, the flow can be as much as seven fold (say like running), while this is of course not necessarily bad for us (increased respiration equals increased thoracic pump, always a plus), at some point it will be out of equilibrium, there just wont be enough throughput to stave off fatigue and oxygen deprivation, of course this is dependent on the individual, location of the stenosis or valve issues and who knows what else.
The flow of blood through the vessels of the circulatory system is a function of the pressure in the system and the resistance to flow caused by the blood vessels. Blood flow is directly proportional to pressure and inversely proportional to resistance.
If the pressure in a vessel increases then the blood flow will increase. However, if the resistance in a vessel increases then the blood flow will decrease.
Resistance in the blood vessels is effected by three parameters:
1. Length of the vessel. The longer the vessel the greater the resistance.
2. Viscosity of the blood. The greater the viscosity the greater the resistance.
3. Radius of the vessel. The smaller the radius the greater the resistance.
Of all of the factors that effect blood flow, the radius of the blood vessel is the most potent. Blood flow is proportional to the 4th power of vessel radius.
This means that if the radius of a blood vessel doubles (by vasodilation) then the flow will increase 16 fold (2 to the 4th power is 16). On the other hand, if the radius of a vessel is reduce in half (by vasoconstriction), then the blood flow will be reduced 16 fold. Because small changes in vessel radius make very large changes in blood flow, it is no surprise that the body controls blood flow to specific areas of the body by controlling the radius of arterioles servicing those areas.
Gotta go but this is so fascinating to toy with in the mind, I keep up on my celphone at work all day when there's down time.
Toss in your garden variety vasoconstiction contributors beyond just physical stenosis/valves etc. and it's really no wonder some of us are so fatigued, I think we all get that this doesn't explain everything in everyone, but it sure does seem to cover enough of a LOT of us, that to suffer like this for one more day than necessary seems so unnecessary, of course in that perfect world where we go in once, get our veins fixed and skip off into the sunset... sigh.