Canada to start CCSVI Trial

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Canada to start CCSVI Trial

Postby MrSuccess » Wed Jun 29, 2011 12:28 pm

news flash . The Canadian Government has jusy announced the funding of a CCSVI-MS trial.




Mr. Success
User avatar
MrSuccess
Family Elder
 
Posts: 883
Joined: Fri Sep 18, 2009 3:00 pm

Advertisement

Postby PCakes » Wed Jun 29, 2011 12:33 pm

Thanks Mr S!!

http://www.ctv.ca/CTVNews/TopStories/20 ... py-110629/

The Canadian Press

Date: Wednesday Jun. 29, 2011 3:18 PM ET

OTTAWA — Health Minister Leona Aglukkaq is giving the go-ahead for clinical trials of a controversial treatment for multiple sclerosis patients.

Aglukkaq says the federal government will fund trials of the so-called liberation therapy in spite of some recent studies that have cast doubt on narrowed neck veins as the primary cause of multiple sclerosis.

The minister says a scientific working group established by the federal government last August has agreed unanimously that a clinical trial should proceed "at the Phase 1 and Phase 2 levels."

Narrowed neck veins -- or chronic cerebrospinal venous insufficiency -- became the subject of numerous studies after Dr. Paolo Zamboni of Italy theorized it could be a factor in the development of MS.

Zamboni has speculated that reduced blood flow leaves iron deposits in the brain, leading to the neural lesions typical of MS -- and he contends that reversing the condition by unblocking neck veins using balloon angioplasty could help alleviate symptoms.

Many hopeful Canadian MS patients have gone abroad seeking the procedure, which isn't offered in this country.

However, some clinical studies -- most recently by a team at the University of Buffalo -- have indicated that CCSVI does not have a primary role in causing MS.
User avatar
PCakes
Family Elder
 
Posts: 849
Joined: Sun Dec 13, 2009 4:00 pm
Location: Canada

Postby Cece » Wed Jun 29, 2011 12:43 pm

great news!!
Cece
Family Elder
 
Posts: 8957
Joined: Mon Jan 04, 2010 4:00 pm

Postby Blaze » Wed Jun 29, 2011 1:14 pm

Does anyone know what a Phase 1 and Phase 2 means? I don't like to be skeptical, but I would love to know why the panel which last August unanimously rejected clinical trials now "has agreed unanimously that a clinical trial should proceed to the Phase 1 and Phase 2 levels."

This is still a long way from treatment being widely available, but it's a step in the right direction (I hope!).
User avatar
Blaze
Family Elder
 
Posts: 405
Joined: Sun Jun 27, 2010 3:00 pm

Postby MrSuccess » Wed Jun 29, 2011 1:27 pm

Blaze .. don't look in the mouth of a gift horse ......



Mr.Success
User avatar
MrSuccess
Family Elder
 
Posts: 883
Joined: Fri Sep 18, 2009 3:00 pm

Postby PCakes » Wed Jun 29, 2011 1:32 pm

Blaze wrote:Does anyone know what a Phase 1 and Phase 2 means? I don't like to be skeptical, but I would love to know why the panel which last August unanimously rejected clinical trials now "has agreed unanimously that a clinical trial should proceed to the Phase 1 and Phase 2 levels."

This is still a long way from treatment being widely available, but it's a step in the right direction (I hope!).


Some good info here... http://ccsvi.ca/research/explained.html
User avatar
PCakes
Family Elder
 
Posts: 849
Joined: Sun Dec 13, 2009 4:00 pm
Location: Canada

Postby Lyon » Wed Jun 29, 2011 1:41 pm

..
Last edited by Lyon on Wed Nov 09, 2011 8:47 pm, edited 1 time in total.
Lyon
Family Elder
 
Posts: 6063
Joined: Wed May 03, 2006 3:00 pm

Postby PCakes » Wed Jun 29, 2011 1:50 pm

updated CTV article... http://www.ctv.ca/CTVNews/TopStories/20 ... py-110629/

CTV.ca News Staff

Date: Wed. Jun. 29 2011 4:27 PM ET

The federal government says it will fund clinical trials into the controversial multiple sclerosis treatment known as the "liberation therapy."

Federal Health Minister Leona Aglukkaq made the announcement Wednesday afternoon during a news conference on Parliament Hill.

Aglukkaq told reporters the government came to its decision after a scientific working group it convened last summer determined during a meeting on Tuesday that a Phase 1 and Phase 2 clinical trial should proceed.

"I have asked CIHR, the Canadian Institute of Health Research, to establish the terms of reference for this clinical trial," Aglukkaq said. "And we are committed to launching an open and transparent call for proposals, and process applications, as quickly as possible."

The liberation treatment was developed by Italian physician Dr. Paolo Zamboni and is based on his theory that narrowed neck veins are behind MS symptoms.

The condition, chronic cerebrospinal venous insufficiency, or CCSVI, reduces blood flow and allows iron deposits to build up in the brain, Zamboni says.

The treatment he developed uses balloon angioplasty to unblock the veins in the hope of alleviating symptoms.

While Zamboni's research has demonstrated success with the treatment, recent clinical trials have concluded that CCSVI is not a primary cause of MS.

The controversy surrounding both the condition and the treatment has not deterred Canadian MS patients from rallying across the country over the last several months to call on both Ottawa and provincial governments to fund the treatment, which is not available in Canada. Many Canadians have had the procedure at medical clinics overseas.

Aglukkaq said the working group was established last August and tasked with reviewing the latest research and making its recommendation to government. The group met in November and again on Tuesday.

Dr. Alain Beaudet, president of the Canadian Institutes of Health Research, said Wednesday that an analysis of all the research done on CCSVI so far suggested "a trend to an association between the greater prevalence of CCSVI in patients with MS than in healthy controls."

Beaudet said more results are needed, particularly from seven current studies, to strengthen the committee's conclusion.

"But, nonetheless, the committee felt that, on the basis of this preliminary evidence and what's published so far, that we should in parallel start already with a Phase 1-2 trial," he said.

During her Wednesday news conference, Aglukkaq hailed MS patients and their families for their struggle with a disease that can lead to symptoms that include difficulty walking, vision problems, fatigue and weakness.

"It has been a moving experience to meet many of you and to hear from so many MS patients and their families who have shown tremendous courage in the face of such difficult illness," she said.

W00T!!!!!
User avatar
PCakes
Family Elder
 
Posts: 849
Joined: Sun Dec 13, 2009 4:00 pm
Location: Canada

Postby Blaze » Wed Jun 29, 2011 2:01 pm

MrSuccess wrote:Blaze .. don't look in the mouth of a gift horse ......



Mr.Success


I know, but we've been disappointed so many times before. Below is another another article from Toronto Star where it says CIHR won't even be putting out calls for proposals until the end of the year. Dr. McDonald is ready to go with a proposal. We need to let him get on with it.

http://www.thestar.com/news/canada/poli ... -treatment
User avatar
Blaze
Family Elder
 
Posts: 405
Joined: Sun Jun 27, 2010 3:00 pm

Postby MrSuccess » Wed Jun 29, 2011 3:37 pm

blaze- I hear what you are saying . we do NOT need a situation as in Italy ..... where the Italian MS Society royaly pissed off Dr. Zamboni by bastardizing [ or freedmanizing :twisted: ] his methods to the exasperation of Dr.Zamboni.

Expect mark freedman to try this . C**k S****r . :twisted:

CCSVI advocates must stay vigilant .... and insist Dr. Zamboni has a major role in the Trials.

This is exciting. We live in interesting times.


Bring on the Brave Dreams ! :!: :!: :!: :!:




Mr. Success
User avatar
MrSuccess
Family Elder
 
Posts: 883
Joined: Fri Sep 18, 2009 3:00 pm

Postby Jugular » Wed Jun 29, 2011 3:45 pm

The provisional results from the 7 studies must have been pretty compelling for this to occur. The CIHR expert panel were unanimously in agreement in September of last year that the current state of research did not justify clinical trials.

From September, 2010

There was unanimous agreement from the scientific experts that it is premature to support pan-Canadian clinical trials on the proposed "Liberation Procedure," said Dr. Beaudet. "There is an overwhelming lack of scientific evidence on the safety and efficacy of the procedure, or even that there is any link between blocked veins and MS.


And today

The group of neurologists, radiologists, vascular surgeons and other researchers met in Toronto on Tuesday and concluded that a meta-analysis of preliminary results of those seven ongoing diagnostic studies as well as the latest published research showed enough of a link between what Zamboni called Chronic Cerebro-Spinal Venous Insufficiency (CCSVI) and MS that further studying the liberation treatment is warranted.

“It permits us not to lose any more time,” said Dr. Alain Beaudet, president of the CIHR.


Holy About-Face Batman!!!

:D 8)
User avatar
Jugular
Family Elder
 
Posts: 375
Joined: Mon Dec 21, 2009 4:00 pm

Postby MrSuccess » Wed Jun 29, 2011 6:35 pm

Invite Dr. Zamboni and Dr. Hubbard to Ottawa ..... ask them how to set this up.

It's that simple. :idea:



Mr. Success
User avatar
MrSuccess
Family Elder
 
Posts: 883
Joined: Fri Sep 18, 2009 3:00 pm


Return to Chronic Cerebrospinal Venous Insufficiency (CCSVI)

 


  • Related topics
    Replies
    Views
    Last post

Who is online

Users browsing this forum: No registered users