This Is MS Multiple Sclerosis Community: Knowledge & Support

I can relate. I feel like my brain is is slowly being cooked.

Hi!



Now this is what the researchers should researching.




Fiona

I had very bad heat intolerance when I had my biggest relapse ever anumber of years ago. Since then, I always felt better when it was 20C or less.

January 2010 I started up with Niacin (vit B3) and in the summer of 2010 I went to south east asia (for a reunion, I would not have made such a long trip to such a hot place otherwise).

Obviously I was dreading the heat but actually I was fine. I did some googling on Niacin and heat intolerace and I found some studies on Niacin and heat stress in live stock (hope I do not offend anyone)

As it happens Niacin drops the core temperature of cattle making them better heat resistant. Google Niacin and heat stress and you'll get loads of info.

http://en.engormix.com/MA-dairy-cattle/ ... 579/p0.htm

Although I still dont feel great when it's real hot, it is definately better. Might be something to try for people who struggle with heat.

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dx 2002,RRMS,  suspected begin of MS 1978 (age 10)

I found this.

Circulation
Niacin promotes healthy blood circulation by causing blood vessels to expand, or dilate. Taking niacin as a supplement might improve blood flow to your skin.

That is correct Dania, I started taking it for that reason. There's been a number of discussions about it here on Tims - it is a tricky vitamin to take, for those interested this might be worth a read:

http://www.thisisms.com/ftopic-14173-da ... asc-0.html

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dx 2002,RRMS,  suspected begin of MS 1978 (age 10)

Well this upcoming week is going to be a real struggle. According to The Weather Channel, the midwest is headed for high 90's and high humidity readings.

Hope my room air conditioner can handle the heat as I am planning to stay indoors.

Donnchadh

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Kitty says, "Take that, you stenosis!"

Got MS?.....Get Liberated!

Be carefull with niacin. It can cause cause the blood vessels in your skin to open and allow so much blood flow that your skin feels like it's on fire. First time I tried it my skin turned beet red and I felt like I was on fire. I had to jump into a cold shower to cool off. Scared the heck out of me since I wasn't expecting that.

When I tried it for the first time, years ago I had the same reaction. I took a 500mg tablet. Far too much. You should start with 25mg. See how you tolerate it.

my neurologist explained MS heat intolerance to me a few years ago ('bout the only thing he's done for me of real use!)
Nerve insulation/myelin is a fat and behaves, apparently a bit like butter when left in the heat and out of the fridge
It's why not just people w MS have heat intolerance.
When the 'butter' melts messages get sent slower... in areas of existing scarring it's doubly so.

If that were the case, though, I would expect heat intolerance to be more permanent and not improve after CCSVI treatment.

Heat also has effects on the vasculature. Sweating is controlled by the autonomic system which may start working better after CCSVI treatment which adds to the heat tolerance improvement cycle.

that's really interesting, I can see that all these factors go into the mix of MS symptoms.

Before i had a car with a/c i couldn't comfortably (or safely) drive for any length of time in the summer without an icepack down my back.

I do feel though that a contributory factor to heat intolerance is neatly described by what happens to a saturated fat in the heat which goes solid again when out of the heat.

Neatly but disturbingly described! I do not like the thought of my brain melting like butter.

60,000 miles of endothelium in one human. Almost all of it controls smooth muscles. Smooth muscle layer in veins and arteries controls what is likely the most powerful mechanism in the body, the diameter of the tubes through which bodily fluid flow. The resistance to flow is proportional to diameter times diameter times diameter times diameter of those tubes.

The veins in the brain, so I am told, have no smooth muscle.

We are liquid cooled engines. Keep hydrated with cool liquids.

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"Try - Just A Little Bit Harder" - Janis Joplin
CCSVI procedure Albany Aug 2010
'_MS' is over - if you want it
Patients sans/without patience

my neuro never sugarcoated anything but I s'pose at least butter goes hard again!

going a bit off topic but what i don't understand is how the brain, which apparently benefits from the right balance of omega 3 & 6 (non-saturates) yet still behaves like a tub of lard/saturate!

A hot brain needs more oxygen and glucose , as the metabolic rate at the brain cells mitochondria is higher. Since the oxygen level demand can not be met the patient experiences desire for escaping he heat.

Could one of you that has had venoplasty but a cold pack on the back of you neck and see if cooled blood helps the sensation abate? I am very curious.if you don't have a cold pack use a bag of frozen peas in a thin covering like a pillow case.

I am very curious...

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Cat (Catherine Somerville on FB)
MegansMom
My 35 yo daughter is newly dx 8/19/10 (had 12 symptoms)
Dx with Type A CCSVI- 1 IJV & double "candy wrapper" appearance of her Azygos
Venoplasty done Sept 21, 2010
Doing extremely well-