Again, focusing on studies based on Doppler ( operator dependent ) studies gives a very biased result that is not good. It shuts the door rather than asking for more study.
A better gauge to measure CCSVI AND IT'S TREATMENT is Dr David Hubbard's objective before and after study of the brain perfusion done with fMRI BOLD.
fMRI BOLD cannot be altered. It's much like a "thinking" pet scan done before venoplasty and after ONLY IT USES OXYGEN NOT GLUCOSE.
It clearly shows the increase in the oxygen level to the brain TISSUE during "thinking" AFTER VENOPLASTY. Objective Evidence of increased perfusion!
One must look with a critical eye at operator technique based studies ( like those cited in this article) especially when the sponsors have support from pharmaceutical companies.
These "do they have CCSVI?" tests are pointless if they are not venoplasty or IVUS based.
DOPPLER TESTING IS NOT RELIABLE ! THE GOLD STANDARD IS VENOGRAM!
Too many patients have been tested, deemed negative and then with further testing and venogram HAD CCSVI!
This Reuters writer has not done her homework. Wait until Dr Oz shows the Montel Williams CCSVI testing and treatment/procedure. After that the dam will burst.
CCSVI may ultimately not be the whole cause of MS. But it does exist and it does need treatment. Treatment does need to get honed and research needs funding. PERIOD!
So why should Zamboni be taken serious? Didn't he use Doppler???
Taken seriously ? Are you kidding? He deserves a Nobel prize !
Zamboni was studying arterial flow via color Doppler . These tests show red as oxygenated blood and blue as deoxygenated venous blood and he noticed that people with MS had reflux (which looks purple) After he saw this finding a few times he thought it warranted more study. He had amn interest and knew more about MS than the average vascular physician. In looking more deeply into this he discovered more similarities to venous disease. The tissue type, the iron deposits, etc. He pent many years prior to his study in 2008/09. The reason Doppler is used for screening is that it's non invasive and cheap BUT and this is a big but, it has limitations if the technician s not trained. Also the Azygos is not visible with Doppler.
But putting the diagnosis of CCSVI aside , please look at Dr Hubbards study. seriously it is the most impressive proof that hypo-perfusion ( low fuel) is caused by CCSVI and chronic HYPOPERFUSION can cause global brain damage, demyelination and cell death.... Which would lead to activation of the immune system, along with a reason for higher than normal brain iron deposits, which can cause oxidative inflammation, and damage of the BBB too.
It all fits.
You can be skeptical but please look at the objective tests- hence Hubbards fMRI BOLD.
HIS FINDING ARE OBJECTIVE PROOF.