At the present time, anecdotal reports continue to surface about the positive changes reported by patients after endovascular treatment of stenoses within the IJ and azygous veins. However, one can in no way state that enough research has been done to conclude that CCSVI is a true pathologic entity occurring with an increased frequency in MS patients, that this entity is responsible for the symptoms and disease progression seen with MS, and that treatment significantly improves the quality of life in these patients. As a result, additional research is going to be critically important moving forward.
This sentiment was echoed in the recent report from the Research Consensus Panel convened by the Society of Interventional Radiology Foundation, which supported the need for additional well-designed studies in areas including basic science work to better understand the relationship between venous stenoses, hypertension, and CCSVI; single-center studies to define appropriate patients to treat and develop standardized procedural technique; and multicenter, prospective, randomized trials to demonstrate efficacy.34 Ongoing studies include registries in Europe and the United States as well as several prospective single-arm and randomized, blinded studies. Ultimately, these studies will help grow our understanding of CCSVI and help determine what role treatment of this entity can and should play in the care of patients with MS.
I'll never forget Jeff explaining what happened to him on the table...he had nothing to go on, he hadn't watched any you tube videos, or read any testimonials. He's not especially suggestable, had no idea what to expect. And he was the first....
"I asked Dr. Dake, what did you just do to me, and he said "Why? Everything OK?"
And I said, yeah, it's great. Everything is clearer; my vision, my brain...it all feels different. I'm awake!
And he said, "I just opened up your right jugular vein."
Not sure how an MRI will ever capture that.