Dr. Siskin gave me tPA on a balloon catheter when I restenosed. It's a drug that breaks up clotting and helps the vein heal after clotting and before stent placement for added adhesion.
It is very much the same as Paclitaxel is for clot disolving
I am confused by this statement. Paclitaxel binds to microtubules and stabilizes them. This induces their polymerization. Microtubules are normally dynamic. However, once stabilized by Paclitaxel, they cannot reorganize into the spindle apparatus. This would block cell division and would be a useful method for inhibiting intimal hyperplasia, excessive cellular growth, as previously indicated.
You are correct NHE, thanks for bringing this to my attention. They are not the same drugs or have the same method of action.
That said, I had a stent previously placed in that left IJV, only days before, and it occluded. My first Venogram showed many intraluminal webs, valve abnormalities and more.
So thrombosis was assumed with US finding of no flow. Vein is occluded. Also it happened quite quickly within days. Until an additional Venography showed the persistent thrombus was caused by a small flap above the stent after the valve issue.
So indeed, neointimal hyperplasia. TPA was given, angioplasty right away, no help, so two more stents and more angioplasty, gave me antegrade flow and the procedure was decided to be terminated and anticoagulation would be used to minimize occlusion of the newly placed stents.
These two new stents overlap the first one on top and bottom.
I have flow but still a bottle-neck in the vein at the top of the stent. Perhaps pressure outside the vein is causing this, i.e. a bone. JMO
I know I need another Venogram, I had three US's. I just need to save for it since my crap ins thinks it's exploratory. I may have recourse now that local Vascular doctor, determined I had a need for one.
Sorry for the long explanation, are you still confused? I am. There is so much to learn. The more I read my reports the more confused I get.
This is all the left internal jugular, where many people seem to have trouble. Not to say the right jugular in okay now, a value leaflet on the low end needs another look. (sigh)