This Is MS Multiple Sclerosis Community: Knowledge & Support

A trigger for the formation of myelin can produce help for those with MS.
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Here's the link to the story on MSRC:

http://www.msrc.co.uk/index.cfm/fuseact ... ageid/2479

Promising news but...

I always thought that the oligodendrochytes were dead (in CCSVI or MS) and that's part of the reason for the myelin loss. This doesn't seem like it would work in the absence of living oligodendrocytes. What am I missing?

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If you can't explain it simply, you don't understand it well enough. - Al Einstein

Very interesting, seems to contradict what other studies have said about glutamate - that it was a bad thing. here's a link:

http://www.medicalnewstoday.com/releases/148291.php

So what does that mean for us? Is the problem that we cannot get this catalyst close to the areas where there is demylenation?

Many have already questionned the autoinmune adjective olaced on MS. I tend to think that also demyelinating adjective should be given a critical review for it might be misleading towards an efective therapy. Within a 1mm3 lesion (a small one in general )seen as white spot on MRI there might be around 100,000 cells. It is strange to think that machine paints them white JUST BECAUSE myelin is absent/broken while rest of the tissue is relatively OK. Intriguing.
Thoughts?

Gauchito,

Here's a decent explanation about what lesions are and what shows up on MRI:

http://www.medhelp.org/posts/Multiple-S ... how/257094

I gather it's more about increased blood flow to the lesion and not damaged myelin directly makes lesions light up.

_________________
If you can't explain it simply, you don't understand it well enough. - Al Einstein

It's essentially a small edema spot? Or do I have that wrong?

It has been an error all along to consider MS only a demyelinating disease, since grey matter is damaged also, early in the disease process.

Dania,

I havent read any of it, but how can they establish, meylin damage, let alone repair as they can only confirm after autopsy after death Yeah!


Fiona

Hi Fee. Interesting question. I neither agree or disagree with the article. Just wanted to share it. Thought some may find it interesting.

i was thinking it was opposite, nerves lack of signal ability to get through starts the bodies reaction to clean up a useless nerve vs the body attacks the nerve first then causing nerve degeneration

put it simply
i think - nerve lack ability to get through. immune is cleaning up useless nerves resulting in myelin and axion death

traditional - immune system cleaning up nerve(autoimmuity) causing signal loss and nerve axon degeneration

my thought process came from
http://www.madsci.org/posts/archives/20 ... .Ns.r.html

because i thought my leg was just dead weight but i can still move it semi fine when im stretching which i find against the whole autoimmune killing off the nerve connection, its weird

civickiller,

Its your right leg yeah!


Fiona

yes right leg how did u know?

Civickiller,

Because my right leg is my worst, but I presume as I straighten it will rectify. You see my problem now is mostly the sciatic nerve which effects my right leg so I cant straighten it at the mo.
But you know a misaligned atlas can cause sciatica, and causes leg to be shorter than the other, I think it also causes dropped foot.

Do you get sciatic nerve pain in the lower back?

Fiona

Fiona,
i do have very bad lower back pain but how do i know if its sciatic nerve pain or not? I do get relief from the lower back pain with an adjustment.

MO ?

ive never heard of sciatic pain associated with a misaligned atlas

Civickiller,

My chiro didnt tell me. I googled....dr windman atlas....I cant paste it to you 'cause of copyright.

She was one of several reasons why I have persued the Atlas thing.

You will find human diagram very interesting, as to the shortening on right side, plus her list of symptoms smacks of familiarity to many ms symptoms yeah.

I've got some other info for you that will help, but this is a start ok

The pain from sciatic nerve for me is a burning soreness, very different from the pain I used to get from the lower back twisting of the spine, that pain has gone and been replaced or it has always been there the sciatic pain.

By the way did you get my email address?

Fiona