This Is MS Multiple Sclerosis Community: Knowledge & Support

The association between EBV infection and CCSVI has not yet been explored; however, it could be hypothesized that venous stasis in the SSS due to extracranial outflow impairment could affect the drainage of bridging veins that pass through the subarachnoid space (near the meninges and EBV-infected B-cell follicles) and contribute to EBV activation. The venous stasis hypothesis in the SSS may contribute to understanding why so many different viruses and bacteria [3,111] have been linked to increased MS susceptibility risk over the last 50 years.