Jugular, THANK YOU for keeping the ball rolling on digging up information. This reminds me of these first years when CCSVI was just becoming known, and lots of people would find--and still are finding--current and old research that would help support the theory of CCSVI.
We need more people to help search for information on Daflon -- I always thought we need to know how strong or weak Daflon's vasoconstriction effect is on veins...
I would think that a vasoconstrictor would hurt, not help, us.
We haven't yet seen any scientific data that shows just how strong or weak Daflon 500 is as a vasoconstrictor--if you know of any such data, please share, thank you!
When you say "us" in the quote above, we need to differentiate between (what I call) "Valvular CCSVI" (annulus and leaflet stenoses) which comprises the MAJORITY
of cases and "Non-Valvular CCSVI" which comprises the minority of cases (e.g., vein wall, high jugular, and compression stenoses).
Since the majority of pwCCSVI has stenoses of the valves, the important anti-valvular remodeling
effect of Daflon has the potential to help a great many MS/CCSVI patients. The truth could be that the many beneficial effects of Daflon far outweigh its vasoconstriction effect. We just don't know yet how the cards will fall.
We should keep trying to find and critique scientific data before turning away too quickly from this promising compound that's easy to take and inexpensive ($.
36/pill). Daflon 500 could be a very powerful adjunct to CCSVI procedures.
Just think of what this could mean--inhibition
of a PROGRESSIVE IN
CREASE in valvular remodeling. In the history of CCSVI, has anything else like Daflon 500 ever been found that already
has been shown in an animal study to decrease annular remodeling???Hypothetical example:
Four months ago, Patient Y, who has "Valvular CCSVI," had her first CCSVI procedure with both IJV valves angioplastied. Improvements were short-lived. Her second procedure was done today with both IJV valves found to be 60% restenosed. Her IJV valves were angioplastied again, BUT THIS TIME, the patient will take Daflon to help slow/stop valvular remodeling and its associated reflux.
After consultation with her doctor about all supplements, the patient will also take the vasodilators quercetin and bromelain to help offset whatever the vasoconstriction effect is of Daflon.
Patient Y could easily be you, Cece. The possibility of forestalling a third procedure or maybe even preventing one with Daflon is worth at least some amount of time spent investigating the compound before dismissing the possibility that the benefits of Daflon might outweigh its risk.
Cece, I'm very surprised you're not much more excited about Daflon, especially considering the above hypothetical. I'd love to see a study done immediately to answer the question of whether or not Daflon's anti-valvular remodeling benefit plus all its other benefits outweigh whatever its vasoconstriction effect might be.
I'd volunteer in a heartbeat for such a study because I have "Valvular CCSVI" with valvular restenosis that the anti-valvular remodeling of Daflon might slow/stop--I really don't want to have a third, or fourth, or fifth, or more procedures.
Patient Y is also benefiting from CCVBP (aka UCC) to relieve pressure on and compression of nerves, arteries, and veins which results in her benefiting from a multipronged strategy for a multifactorial disease that would look like this: 1) CCSVI venoplasty to decrease venous insufficiency and reflux, 2) Daflon 500 to decrease valvular remodeling and reflux, and 3) UCC to correct Atlas misalignment for proper CSF flow and decompression of nerves, arteries, and veins.
CCSVI had given me hope and several good improvements, but I restenosed six months after each valvuloplasty.
UCC still gives me hope because my properly adjusted Atlas resulted in a "notable" increase in my CSF flow and because my numb feet and 'MS' Hug symptoms are greatly relieved, 100% and 75%, respectively. I remain hopeful for even more improvements as time continues.
Daflon 500 is giving me a measure of new hope for my venoplastied IJV valves. Wish me luck with my Daflon 500 literature review (good links gladly accepted!) because the majority of pwCCSVI might benefit greatly and that thought alone, imo, is worth my effort.
If Daflon doesn't pan out, I'll continue to look for more hope and help for my ongoing neurological symptoms.
Cece, help us research this compound. Look at all the information that has been found so far--let's go find more! Let the hunt continue!
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