Won't reflux affect shear stress? I think they are saying it may, and that this could be bad for the BBB. Why are MS veins disappearing? Maybe the effect of the higher pressure pre the stenosis is causing more shear stress in the veins upstream.
Shear stress seems very important in blood. We think we know how
shear affects blood vessels, and at the site of a defect there may be more shear. They are calling it "reactionary remodeling of affected blood vessels. "
I think Dr. Simka wrote about how shear also affects the stuff that makes leukocytes stick to blood vessels. I thought (wrongly?) that since it is a low pressure system there might not be any turbulence. I guess maybe though it's a lower value normally, maybe veins are more sensitive to shear than arteries, and a change can have a much greater effect. Idle speculation.
I found out, along the way that
blood viscosity varies as expected with temperature. But because hematocrit (number of red cells) and vessel diameter (capillaries are different) affect viscosity, the temperature/viscosity relationship is not easy for me to figure out.