AHA: Drug-Coated Balloons Expand PCI Options
ORLANDO -- Drug-eluting balloons can be used in place of stenting in patients at high risk of bleeding, Mariusz Zadura, MD, explains in this exclusive InFocus report.
They are particularly useful for patients on warfarin, Zadura, of the Heart and Diabetes Center in Karlsburg, Germany, told cardiology editor Chris Kaiser.
When drug-eluting stents are implanted, dual antiplatelet therapy is contraindicated for 12 months; when balloons are deployed, antiplatelet therapy can begin a month later.
The balloons also offer a solution for bare-metal instent restenosis, Zadura said.
How do the drug-eluting balloons offer a solution for bare-metal instant restenosis? I'm confused by that. If it's a bare metal stent, there is no elastic recoil, because the stent would prevent that. Does it mean this is a solution for instant restenosis with regular balloons? Not sure how that would work. It doesn't mention what drugs are being eluted but I imagine it's blood thinners concentrated on the site of injury. We've discussed this some here at TiMS, I remember being confused and thinking it was a drug-eluting stent, but no it is a drug-eluting balloon. There could well be a role for drug-eluting balloons in CCSVI because of the push to avoid stents because of complications.
Primary source: American Heart Association
Zadura, M, et al "Drug eluting balloon-PCI is an alternative to drug-eluting stents in patients with a high risk of bleeding complications" AHA 2011; Abstract 10265.
Additional source: American Heart Association
Zadura M, et al "Drug-Eluting Balloon-PCI is a New Therapeutic Option for Patients with In-Stent Restenosis in Bare Metal Stents" AHA 2011; Abstract 10244.
There we go! The drug-eluting balloon is a new option for patients with in-stent restenosis in bare metal stents! There are patients here with in-stent restenosis in bare metal stents. If anyone can access the full article, are they talking about restenosis due to clotting or due to intimal hyperplasia regrowth? Either one could use a solution.
edited to add: lol, it's saying in-stent restenosis, not instant restenosis, in the medpage quote. That makes more sense.