This Is MS Multiple Sclerosis Community: Knowledge & Support

This sounds like a fantastic advancement. I don't think it'll help us much in MS because in MS, axons are not severed, so there's nothing to relink. Wallerian degeneration starts at the end of the axon and degenerates inward toward the neuron.

I don't think that's correct. Axonal damage is characteristic of MS.

See this: Acute axonal damage in multiple sclerosis

--Tracy

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CCSVI Procedure 9/16/2009 at Stanford
Stent in left and right IJVs
SPMS
Copaxone and Ampyra user

I don't know why but the link wouldn't open for me. Axonal damage such as wallerian degeneration is present in MS. You are suggesting that axons are severed in MS? This advancement is specifically a way to get a severed axon to reattach to the neuron body. Typically a severed axon shrivels up and dies, and a new one must be regrown. As I understand it the problem in MS is not that the axons are severed, but that they are damaged. There is not a perfectly healthy axon that needs to be reattached, there is a half dead axon that is attached but not getting the nutrients including oxygen that it needs or that is suffering damage from leukocyte attack.

I jumped to the conclusion that your original post was stating axonal damage is not an important factor in MS, hence the link I added. I agree that the type of axonal damage that occurs with MS may not benefit directly from the recent accomplishment of repair of severed nerves.



--Tracy

I stand corrected!

http://nro.sagepub.com/content/5/1/48.abstract
So axonal transection means the same as severing of the axon.
Now I have to reread the link dania posted. Would there be a possible solution to ongoing axonal severing such as this, or would it only be practical in one-time traumatic instances of axonal severing, such as spinal cord accidents? Would the presence of inflammation interfere with reconnection of the severed axons?

I don't know, but I thought my 'black holes' or hypointense areas on my MRI, were dead areas (no water in dead cells). I thought that was probably due to nerve death. To me the thing that was singular about them was that they were very round, compared to the hyperintense lesions, the perivenous ones. They seemed to have a more well-defined 'sharper' edge. They made my brain look like a sponge-cake. That was one reason I thought it must be caused by a germ of some kind, but what do I know?

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"Try - Just A Little Bit Harder" - Janis Joplin
CCSVI procedure Albany Aug 2010
'_MS' is over - if you want it
Patients sans/without patience