a study on respiratory effects on MR imaging of CCSVI

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

a study on respiratory effects on MR imaging of CCSVI

Postby Cece » Fri Feb 10, 2012 7:27 pm

http://www.jcmr-online.com/content/14/S1/W4
The introduction of the CCSVI hypothesis in the diagnosis of MS has recently caused interest in intra- and extracranial venous flow measurements (1). Due to structural complexity and individual variations, flow studies in cerebrospinal veins using phase-contrast (PC) MR are rarely conducted (2). Though it has long been confirmed a source of variability in venous drainage to the heart (3), respiratory motion effects have been largely ignored in PC-MR, partially due to the difficulty and longer scan times of gating the respiratory and cardiac cycles. The purpose of this pilot study was to implement a dual-gated PC-MR sequence and investigate the effect of respiratory motion during free breathing on cerebrospinal venous flow.

I don't see the value in this study. Breathing affects the MR imaging of the cerebrospinal venous flow....so what can anyone do about that?
Clinically, MR imaging does not seem to be as useful or easy as doppler imaging.
Cece
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Re: a study on respiratory effects on MR imaging of CCSVI

Postby Cece » Fri Feb 10, 2012 7:30 pm

Wait, here's a second study from the same guys. They are in Wisconsin. Was this one of the MS Society's 7 funded studies by any chance?
http://www.jcmr-online.com/content/14/S1/W33
Presented is a novel MR imaging protocol to comprehensively assess vessel lumen and hemodynamics of the cerebrospinal veins. The 3 station exam is designed to cover middle cerebral, jugular, and azygous veins in order to investigate the CCSVI hypothesis for the association of insufficient venous return with multiple sclerosis.
Cece
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