Dr. Robert Fox: Composition of lesions is water. The most important factor is like real estate: location location location
Next up: Dr. Robert Fox "Postmortem assessment of jugular and azygos vein pathology"
Dr. Fox: injected IJV and azygos veins with silicon and removed for analysis. Upper IJVs not extracted.
Dr. Fix: anatomical variation in tri-, bi-, and uni-cuspid IJV valves
Dr. Fox: Valves looked to be normal in function. Hyperplasia sometimes seen (vein narrowings) and abnormal flaps
Dr. Fox: Intraluminal membranes extending 2/3 the way across the vein sometimes found in IJVs
Dr. Fox: intraluminal septum & sheaths found
Dr. Fox: Higher incidence of intravenous abnormalities in MS patients, but no differences in functional abnormalities
What does that mean? Not as much as I'd expected. Higher incidence of intravenous abnormalities, but no differences in functional abnormalities? Valves looked to be normal in function.... Sheaths and septums and membranes were found. The fixing of the veins with silicone may have made it difficult to see if the valves were unnaturally stiff and fixed. How was it assessed that there were no differences in functional abnormalities?
Dr. Fox: Number & location of MS lesions determines disability only in early stages of MS, not in progressive forms