Billmeik wrote:dr fox's interview was great. That's the stuff we should be reading about in the newspaper
1eye wrote:Thanks to cheerleader, we knew about Dr. Fox's work, as soon as it was published. That's one good thing about this place. There almost seems to be a competition to get the best info. I think it's great. The ISNVD interview I found the most earth-shaking was Dr. Alexander's, where he said they have markers for MS that are related to vascular remodeling, involving the state of the endothelium in the veins. To me it was an unexpected deepening of the theoretical side, strengthening the CCSVI theory.
Dr. Alexander is an endothelial and vascular biologist working on how microvascular injury associated with forms of neuroinflammation (Multiple Sclerosis, stroke, Alzheimer’s disease), cancer and Crohn's disease. All of these diseases exhibit disturbances in blood vessel barrier function contributing to tissue edema. Current models indicate that endothelial activation, survival and junctional integrity (tight and adherens junctions) are metabolically regulated and modulate solute and inflammatory cell extravasation during inflammation. A new and important direction in this area of research is the understanding of the significance of endothelial microparticles as predictive markers and mediators of acute and chronic BBB inflammation, particularly in MS and AD.
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