The financial interests declared seem to centre around companies who are vendors of "MS" DMDs. He seems to want to be saying like Dr. Zamboni, keep taking your DMDs. I think it is interesting that he obviously used the word "prevalence" but was quoted as using "prevalent." The difference is that one is technical, and the other could be interpreted as saying these studies prevail.
He is saying the disease of CCSVI exists, but that "up to" 1 out of every 4 people also have it. That is tantamount to the common criticism that these insufficiencies are "normal" anatomical variations, to be expected in normal anatomies. But isn't it true that a) the diagnosis of CCSVI was not performed by people who had ever looked for it before, b) the study was the initial, smaller study, which also showed a lower prevalence of CCSVI in MS than he eventually found, and c) he is now advocating new measures to test for CCSVI that are invasive? I will not pay much attention to the "normal variant" argument, especially when he used relatives of people with "MS", and the MS patients were already showing higher CCSVI.
This interview carries a lot of weight because of his work, but my eyes gloss over when I am told even more money must be spent before we can even diagnose, on SWI, MRI, MRV, IVUS, etc. There's nothing that special about it. If you have MS you should be screened with expert Doppler, and if still unsatisfied, given the high prevalence, only if that test comes back negative should you request further tests. Insurance, if you have it, should pay. There will always be the repeated cry of "more studies!" Whether or not to attempt a diagnosis of CCSVI in normals or people with other neurological diseases is best left to the people and their doctors.
As far as the treatment goes, I think people should not waste time worrying how CCSVI is related to MS; that is for researchers to figure out. If the results from the Saskatchewan study corroborate Dr. Zamboni's papers, on the strength of QoL alone, nobody callng it experimantal will have a leg to stand on. Insurance should at least be asked to honour claims that had previously been refused. If their red tape moves as fast as government studies, the evidence will be plain, before any checks are issued.
I don't wish to demean Dr. Zivadinov, because he has many constituencies to satisfy, and he is obviously as interested in the truth as anyone. Just that everybody needs to remember their salt grains.
He didn't talk about it here, but I think he himself found one of the smoking guns of CCSVI: new veins collateral to the Internal Jugulars in more MS patients than normal. I don't know if figures are available. These do not even form unless the Internal Jugular is insufficient. They are triggered by hypoxia (shortage of oxygen in the venous blood).
"Try - Just A Little Bit Harder" - Janis Joplin
CCSVI procedure Albany Aug 2010
'MS' is over - if you want it
Patients sans/without patience