I don't know, but good questions.
Here's an image of dilatation of the jugular vein in jugular phlebectasia. This is considered a benign condition. If jugular phlebectasia does not compress the vagus nerve, I do not think CCSVI dilatation would. Or am I missing something?http://www.ijoonline.com/viewimage.asp
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i strongly doubt this hypothesis. The pressure in the jugular vein is so low, that it is unlikely to have an affect on the vagus nerve function.
Also the vocal cords are controlled by the vagus nerve and i do not think that patients with ccsvi or m s have hoarse voices very commonly. and that would be affected by vagal nerve in the neck being dysfunctional.
it is far more likely that the cranial nerves are affected by the demyelination intracranially in the brain stem
Dysautonomia is very common in MS but i think its cause is inside the skull
The vagus descends within the carotid sheath, between the internal jugular vein and the internal and common carotid arteries.
They all three run in parallel in sheaths, one on each side of the neck. What if the carotid were expanding in the sheath? Is it above or below the usual place for stenosis? If above, the vein being the next least compressible, there might be two effects:1) compression of the vagus and other nerves co-located alongside the two blood vessels, and 2) forcing of venous blood backwards, upwards, away from the stenosis and towards the BBB
The whole thing reminds me of something. After the 6-month episode in 1982, which resolved completely, and was nothing but intention tremor on the right and slight dizziness, my first symptom and sign of what was to come, was a numb left pinkie finger. That happened the next day after I had spent a weird night almost sleeping on a couch with wooden arms. I spent the entire night trying to use one of the arms as a pillow. Unfortunately my whole weight almost was taken by the corner of the wood, which was not a good pillow.
I had had one side or the other of the middle of my neck resting on the corner. I could feel the blood in my head backing up, so after a while, I would change sides, just to keep it even. The next day, my neck was not sore, but my pinkie was numb. Unlike any instance of an arm "falling asleep", the sensation never came back
. It's still gone.
That was 1989. Pins and needles was all I felt in that digit, from then on. Many other symptoms came and went until I finally got diagnosed in 1997.