Rica, who posts as Katman is the best example of someone with primary progressive disease who was successful. Either look her up here or go to CPn Help, all one word, dot org where you will find her nearly every day: she has forgotten her password here, I think!
An Itinerary in Light and Shadow Completed Dr Charles Stratton / Dr David Wheldon abx regime for aggressive secondary progressive MS in June 2007, after four years. Still improving with no relapses since starting. Can't run but can paint all day.