Seven studies, running over their two year deadline, with inconclusive somewhat negatively presented results.At this point, no connection has been confirmed between CCSVI and MS, in fact, CCSVI appears to occur in many people who do not have MS.
Title: “A Multi-Modal Assessment of Chronic Cerebrospinal Venous Insufficiency”
Robert J. Fox, M.D.
Cleveland Clinic Foundation
Term/Amount: 7/1/10-6/30/12; $571,261
A series of recent publications have suggested that some people with MS have obstructions in the veins that drain blood in the brain and spinal cord that may contribute to nervous system damage in MS.
Dr. Fox and a multi-disciplinary team are seeking to reproduce these findings in 90 people with MS and 80 control subjects without MS, using various tests, as well as examining vein tissues obtained via autopsy.
Data from these studies will provide a comprehensive foundation upon which to either design further longitudinal and intervention studies, or reject this hypothesis of MS pathogenesis.
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