Cochrane Review-Well-designed/robust studies are warranted

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Re: Cochrane Review-Well-designed/robust studies are warrant

Postby 1eye » Tue Jan 15, 2013 9:49 am

What they allow in the UK should not affect trials done in North America. I would be surprised if the Albany/Saskatchewan trial does not offer sedation.

I don't think they are waiting for this forum to figure it out, or arrive at technical preferences, or decide when it's OK to start.

According to the government web site, isn't the registry kaput?
"Try - Just A Little Bit Harder" - Janis Joplin
CCSVI procedure Albany Aug 2010
'MS' is over - if you want it
Patients sans/without patience
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Re: Cochrane Review-Well-designed/robust studies are warrant

Postby MarkW » Thu Jan 17, 2013 3:15 am

1eye wrote:What they allow in the UK should not affect trials done in North America. I would be surprised if the Albany/Saskatchewan trial does not offer sedation.

I am sure the Albany researchers are considering the publically stated opinion of a leading CCSVI expert and Professor of Inventional Radiology in New York State who says it is better to have an awake patient during the procedure. It is highly likely that the Ethics Committee who have to approve the study will be aware of DrS's opinion.
It is a mis-conception that a robust trial must be single or double blinded. The NICE guidance in the UK made this clear for UK trials.
Kind regards,
MarkW
Mark Walker - Oxfordshire, England. Registered Pharmacist (UK). 11 years of study around MS.
Mark's CCSVI Report 7-Mar-11:
http://www.telegraph.co.uk/health/8359854/MS-experts-in-Britain-have-to-open-their-minds.html
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