Two new reviews by Dr. M. Dake and Dr. M. Mehta

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Two new reviews by Dr. M. Dake and Dr. M. Mehta

Postby cheerleader » Tue May 07, 2013 1:02 pm

Dr. Dake and Dr. Mehta are featured in the endovascular journal for the 10th International Symposium of Endovascular Therapeutics in Barcelona, Spain. Thanks to CCSVI Alliance for making these reviews available online:
http://www.sitesymposium.org

Historical overview of CCSVI and multiple sclerosis relationship by Dr. Michael Dake
written for the 10th International Symposium of Endovascular Therapeutics in Barcelona, Spain

The publication of these findings unleashed an emotionally intense controversy that currently
still forments with boiling points of view. From highly critical reaction that decry the concept of CCSVI as a hoax that provides false hope to vulnerable and desperate, individuals to supportive testimonials from treated patients, the debate surrounding the existence, association and relevance of CCSVI to MS is reflected in the contributions to the medical literature. Although, the vast majority of the articles on the topic consist of commentaries, opinions, interpretations and diatribes, rather than reports of clinical evidence for or against CCSVI, the essence of the recently published independent clinical studies designed to evaluate various aspects of the CCSVI hypothesis do, by and large, reflect the opposing public contentions in the dispute by presenting conflicting results that either pointedly question, or support the existence of CCSVI. At present, our level of understanding is simply insufficient to settle the argument.


https://www.facebook.com/notes/ccsvi-al ... 5993931099

We Need a Huge Randomized Controlled Trial by Dr. Manish Mehta

written for the 10th International Symposium of Endovascular Therapeutics in Barcelona, Spain


So back to the question at hand, is CCSVI an entity and a subset of MS? On the basis of the significant body of evidence generated from multispecialties across the globe, the answer to that question would be YES. From its initial description, over the past several years, many investigators have continued to add to rapidly evolving scientific evidence that identifies CCSVI association with MS and maybe even other neurodegenerative disorders. As with any new therapy and particularly with MS, the initial learning curve is steep, and many of the publications have emerged without a standardized approach to the diagnosis, intervention, adjunctive treatments, and critical endpoint analysis. It would have been impossible for any single individual, institution, or specialty to discover a phenomenon, invent a procedure, and identify all of its perceived benefits, particularly in a disease state as elusive as MS. Our understanding of CCSVI and its implications in MS patients has evolved significantly over the past several years and today MS societies worldwide are committing millions of dollars to CCSVI related research projects. The ongoing collaborative efforts among national and international multidisciplinary research teams to better understand the implications of CCSVI in MS is underway, and it is likely that this evidence will help shape the future treatment strategies for not just MS patients but also those with a variety of other neurodegenerative disorders.


https://www.facebook.com/notes/ccsvi-al ... 5817229450
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
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Re: Two new reviews by Dr. M. Dake and Dr. M. Mehta

Postby frodo » Wed May 15, 2013 3:55 pm

This is the first time I hear about CCSVI as a subset of MS. This possibility opens also the possibility of better diagnosis and response to medication for the other types, just like the discovery of aquaporin-4 in NMO did before.
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