Blood Vessel Endothelial Cells Can Repair, Regenerate Organs

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

Blood Vessel Endothelial Cells Can Repair, Regenerate Organs

Postby pairOdime » Thu Oct 10, 2013 11:47 am

http://www.sciencedaily.com/releases/20 ... 152218.htm
In studies appearing in recent issues of Stem Cell Journal and Developmental Cell, the researchers show that endothelial cells -- the cells that make up the structure of blood vessels -- are powerful biological machines that drive regeneration in organ tissues by releasing beneficial, organ-specific molecules. They discovered this by decoding the entirety of active genes in endothelial cells, revealing hundreds of known genes that had never been associated with these cells. The researchers also found that organs dictate the structure and function of their own blood vessels, including the repair molecules they secrete.

"Scientists had thought blood vessels in each organ are the same, that they exist to deliver oxygen and nutrients. But they are very different," and each organ is endowed with blood vessels with unique shape and function and delegated with the difficult task of complying with the metabolic demands of that organ, Dr. Rafii adds.

They found that endothelial cells possess tissue-specific genes that code for unique growth factors, adhesion molecules, and factors regulating metabolism. "We knew that these gene products were critical to the health of a particular tissue, but before our study it was not appreciated that these factors originate in the endothelial cells," Dr. Nolan says.
It's a paradigm shift
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Re: Blood Vessel Endothelial Cells Can Repair, Regenerate Or

Postby Cece » Thu Oct 10, 2013 1:44 pm

that's really interesting!
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Re: Blood Vessel Endothelial Cells Can Repair, Regenerate Or

Postby 1eye » Fri Oct 11, 2013 9:50 am

That might be a reason NOT to have the procedure. If only there were a good alternative for SP"MS"...
"Try - Just A Little Bit Harder" - Janis Joplin
CCSVI procedure Albany Aug 2010
'MS' is over - if you want it
Patients sans/without patience
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Re: Blood Vessel Endothelial Cells Can Repair, Regenerate Or

Postby Cece » Fri Oct 11, 2013 2:08 pm

1eye wrote:That might be a reason NOT to have the procedure. If only there were a good alternative for SP"MS"...

I came to the opposite conclusion, that the procedure allows for proper flow, which is healing for the endothelium? Any direct damage to the endothelium from ballooning happens in the lower jugular but the benefit could extend upstream and to the blood-brain barrier.
Also, eat healthy, work out, the usual....
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