misdiagnosed as ms-"another blood flow thing"

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.

misdiagnosed as ms-"another blood flow thing"

Postby blossom » Wed Jan 15, 2014 5:59 pm

although this dr. discovered this i wonder how many dr.'s are really aware or consider testing for this? maybe some of you are already aware of this, it's new to me, maybe others too.

anyway, different than ccsvi, but, still a blood flow thing.

http://articles.chicagotribune.com/2011 ... 1_cells-...
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Re: misdiagnosed as ms-"another blood flow thing"

Postby Cece » Thu Jan 16, 2014 6:22 am

I had not heard of this and it's really interesting.
Let me quote:
Capillaries are tiny blood vessels that branch out from the ends of arteries and deliver blood to tissues. Normally only wide enough for one red blood cell to fit through at a time, the capillaries that create the caverns in the brain become wide enough to accommodate up to 100 red blood cells.

"It's like taking a capillary and blowing on it like a balloon," Awad said. The blown-up capillaries can ooze or leak blood and exert pressure on the brain.

Normal endothelial cells in a dish adhere to one another and form tubes. But the cells missing the CCM1 and CCM2 genes did not stick to one another and leaked. The researchers discovered that the proteins made by the CCM1 and CCM2 genes help stabilize cells by keeping other proteins that can increase the leakiness, particularly a protein known by the acronym ROCK, in check.

This is a drug that inhibits blood-brain barrier leakiness. It's called fasudil. Could it work in MS patients?
This is why I hesitate to rail against Big Pharma, because for all the shady financial-gain non-patient-oriented ethics, we could still really use Big Pharma to be developing pharmaceuticals with the new insights of CCSVI in mind.
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Re: misdiagnosed as ms-"another blood flow thing"

Postby centenarian100 » Tue Feb 04, 2014 3:49 pm

Interesting. Nice find.
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Re: misdiagnosed as ms-"another blood flow thing"

Postby NHE » Wed Feb 05, 2014 5:29 am

Cece wrote:This is why I hesitate to rail against Big Pharma, because for all the shady financial-gain non-patient-oriented ethics, we could still really use Big Pharma to be developing pharmaceuticals with the new insights of CCSVI in mind.


Gamma-linolenic acid also helps strengthen the tight junctions of the blood brain barrier.
natural-approach-f27/topic23977.html#p219686
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