Ashton Embry about the misconducts of some teams

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Ashton Embry about the misconducts of some teams

Post by frodo »

The most recent negative Canadian CCSVI study, lead by University of British Columbia neurologist Dr. Anthony Traboulsee and published in The Lancet, did not utilize the original scientific protocol of Dr. Paolo Zamboni.
http://www.thelancet.com/journals/lance ... S0140-6736(13%2961747-X/abstract

This new study displayed even further arrogance and audacity, by deviating from all other published venous and arterial studies, utilizing a false criteria to assess jugular vein stenosis.

Stenosis is routinely measured by comparing the narrowed segment to the adjacent normal section of vein or artery and expressing this as a percentage. This is the accepted way to measure stenosis. All international vascular researchers use this method.

You can read more here

http://ccsviinms.blogspot.com.es/2014/1 ... nduct.html
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Re: Ashton Embry about the misconducts of some teams

Post by NHE »

frodo wrote:The most recent negative Canadian CCSVI study, lead by University of British Columbia neurologist Dr. Anthony Traboulsee and published in The Lancet, did not utilize the original scientific protocol of Dr. Paolo Zamboni.
http://www.thelancet.com/journals/lance ... S0140-6736(13%2961747-X/abstract

This new study displayed even further arrogance and audacity, by deviating from all other published venous and arterial studies, utilizing a false criteria to assess jugular vein stenosis.

Stenosis is routinely measured by comparing the narrowed segment to the adjacent normal section of vein or artery and expressing this as a percentage. This is the accepted way to measure stenosis. All international vascular researchers use this method.

You can read more here

http://ccsviinms.blogspot.com.es/2014/1 ... nduct.html
I suspect that the Traboulsee paper will set a precedent for other neurologists wishing to "debunk" CCSVI. The Earth really is flat (especially if your viewpoint never ventures outside of Kansas, let's all go to Kansas and see how flat it is).
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Re: Ashton Embry about the misconducts of some teams

Post by AMcG »

I do like your characterization of Traboulsee as the wizard of OZ NHE. It fits. His research is all smoke and trickery. I got the impression from the beginning that he thinks he is Tarzan and all he needs to do is beat his chest with his fists and shout to make people believe him. He has no interest in experimental proof. He tries to rely on his reputation rather than his real intellectual powers and ability to design good experiments. From a serious perspective his research is simply GIGO (garbage in...) It was designed to find nothing significant and succeeded. He then trumpeted it as disproving CCSVI. Not surprisingly Zamboni saw through it straight away.

But unfortunately that has always been the case with research. Some is good some is bad. Some is designed with good intent and some is designed with evil intent. We simply have to rely on the wider peer review process to take it's course. This research is garbage and proves nothing and I am confident there are many other researchers and observers who can see that clearly. I think it will eventually become a source only of embarrassment for Traboulsee but that may take a long time.

But worse I am very ashamed and dismayed at the way the Lancet has treated Zamboni's attempts to have his rebuttal aired. That is totally reprehensible and far short of what they should have done, Why not offer Zamboni an opportunity to write a longer discussion piece like they did with Khan et al when Zamboni's 2009 paper came out? Trumpetting Traboulsee's paper as they did last year was ridiculous enough but then refusing to publish a completely damning comment like Zamboni's is too much. The same should be said about Traboulsee's failure to reply to Zamboni's requests. There really should be some way of making an official complaint but I don't now what it is. Do universities have complaints departments?
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Re: Ashton Embry about the misconducts of some teams

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Was this the same bunch that would not even reply to Dr. Sclafani's offer of help, and ignored the known benefits of the use of IVUS? Anyway, it is obvious to anyone with any depth of knowledge in this area how these cards are stacked.

The issue of percent stenosis implies, without actually saying it, that this is a straight-line, linear, one-dimensional problem. No matter how you express it, by caliber, cross-sectional area, diameter or radius, a linear percentage difference does NOT reflect the importance of any alteration in the capacity of a tubular structure to carry liquid. Whatever the size of the alteration, A, the difference that makes to flow rate of blood is in proportion to (A times A times A times A). Four dimensions: length, width, depth, and time. It is hugely more important, to a major blood vessel, than a linear percentage. Drs. Zamboni and Sclafani, and many others, use CSA. At least cross-sectional area has 2 of those dimensions!
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Re: Ashton Embry about the misconducts of some teams

Post by PointsNorth »

Did anyone honestly believe the outcome would be different??? C'mon folks!

The Neuros found exactly what they were looking for AND got the Lancet to publish. Game, Set & Match

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Re: Ashton Embry about the misconducts of some teams

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MrSuccess is not so sure if he should join in on the chorus line bashing Dr.Traboulsee's , CCSVI article in Lancet. No big fan of Dr.Traboulsee here. You can research my post about him. In a nutshell ... I think he is a fox in the Big Pharma henhouse. And I cannot stand that S E G of
his. But that's me.

When Dr.Zamboni published his ORIGINAL study of the 65 people with MS , he suspected had bloodflow problems [ CCSVI ] ..... he concluded his study with asking for
his respected peers to review his work ..... his methods .... and to try to replicate his findings. Dr.Zamboni suggested a LARGE clinical trial would be welcomed.

No smoke ... No mirrors ...

MrSuccess is thrilled that CCSVI has now landed on the pages of Lancet . This was unthinkable not that long ago. This is a victory for CCSVI people. The doubting Thomas'
of the Neuro World are spinning.

As for the numericals in Dr. Traboulsee's small study .... the very FACT that CCSVI was detected in ONE pwMS .... PROVES .... that CCSVI is a condition that exists. Thanks , Dr. Traboulsee ! Another victory for the CCSVI camp .

And finally , we read that 74 % of pwMS do indeed have narrowed major veins. More so , than all other groups. Only 4% more you say ? Insignificent ? Maybe not.
These numbers easily show that CCSVI has a strong tie to MS. Another victory in favor of Dr.Zamboni's theory of CCSVI >>> MS.

What's not to like about this study ?


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Re: Ashton Embry about the misconducts of some teams

Post by AMcG »

Frodo you named Ashton at the top of this thread so I thought you must be referring to an article by him. When I looked for a comment on Direct-MS I could not find one. Is there a comment from Ashton you know off which I have missed? I would be grateful for a link.

I did however eventually find Zamboni's comment which is completely damning about Traboulsee's report. I have said before his results looked to me like they were largely composed of noise and Zamboni has pointed out the reason. If what Paolo says about Traboulsees's technique is true then his results are nothing but noise. This is the comment for those who have not seen it:

Last January The Lancet published the article by Traboulsee et al. Prevalence of extracranial venous narrowing on catheter venography in people with multiple sclerosis, their sibilings, and unrelated healthy controls: a blinded, case control study. These Authors confirmed the presence of chronic cerebrospinal venous insufficiency with a high prevalence of about 70% in the Canadian population, but without significant differences between patients and healthy controls, yet. However, they used a criterion never published to assess stenosis, in alternative to the classic measurement of the diameter in the segment immediately preceding the narrowest point. Traboulsee et al. measure the stenosis along the entire length of the internal jugular vein, by comparing the maximum diameter with the narrowest point. It has been demonstrated, from normal anatomy findings, how the jugular bulb diameter normally exceeds 50% of the minimum diameter of the internal jugular vein, clearly showing the reason why Traboulsee et al. did not find significant differences between people with multiple sclerosis, their sibilings, and unrelated healthy controls. Furthermore, as the outcome measure of Traboulsee et al., wall stenosis is a neglected part of primary venous obstruction, because in the majority of cases obstruction is the consequence of intraluminal obstacles, as a considerable part of truncular venous malformations, and/or compression; rarely of external hypoplasia. Finally, several recently published methods can be adopted for objective assessment of restricted jugular flow in course of chronic cerebrospinal venous insufficiency, by the means of non invasive magnetic resonance imaging, ultrasound and plethysmography. This may help us in improving the assessment of cerebral venous return in the near future.
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Re: Ashton Embry about the misconducts of some teams

Post by NHE »

AMcG wrote:I do like your characterization of Traboulsee as the wizard of OZ NHE.
That's not exactly what I meant. Another anaolgy: If you walk around wearing welding goggles all day, you might report that the world is a very dark place. However, this does not reflect reality. Traboulsee's non-standard way of detecting stenosis is akin to wearing welding goggles (or thinking that the world is flat just because you happen to be in Kansas and Kansas looks pretty flat).
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Re: Ashton Embry about the misconducts of some teams

Post by cheerleader »

Hi guys-

I wrote that, not Dr. Embry. Notice the "Joan" at the end? :) Although, Dr. Embry has told me he supports the conclusion--as do a couple of investigative reporters who are now on the case, and many other vascular specialists. There have been stories in the Italian press. This situation is not going to just disappear.

The problem is that the Traboulsee team created an entirely new way of measuring venous stenosis.
Their method has never been used in any published journal.

The team used the entire length of the jugular vein, and compared the widest section at the jugular bulb to the smallest section. That way, they concluded that almost everyone has CCSVI....
but that's not how you measure stenosis!


Please read my whole post...it even has diagrams of the gold standard method for measuring stenosis and more information on how The Lancet refused to publish Dr. Zamboni's letter pointing out this error.

http://ccsviinms.blogspot.com/2014/12/s ... nduct.html

I believe it is scientific misconduct----and I am not alone.
cheer/Joan
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
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Re: Ashton Embry about the misconducts of some teams

Post by MrSuccess »

lot's of good information in your blog, RL . Certainly shows the vast difference between our hero - Dr.Zamboni - .... and that other guy. Night and Day.

In spite of the great cost and effort to undermine CCSVI , this so-called study has in fact been very helpful.

Not that long ago , CCSVI was labeled as fictitious. Now ... our good doctor Traboulsee has confirmed it's very existence. We knew that ....... now you do sport !

Is it safe to treat ? That scare mongering has been put out to pasture. Performed by the right medical people ..... catheter venography is safe ..... even Dr. Traboulsee can do it !

Poor old MrSuccess cannot understand how dear Dr.Traboulsee can detect a rate of 70% of his MS study participants having major vein blood flow narrowing [ 50% or more ] ..... but can see no reason to worry. Are you kidding ?

I hope this guy's urethra ...... contracts to about 50% capacity . :idea:

Maybe his BIG PHARMA backers can supply him with a life time of medication. :lol: to help restore his flow. As MrSuccess wishes no ill will towards those that lack common sense. :peace:

Maybe Dr. Traboulsee has lost Dr.Zamboni's contact information ? I think NASA might be able to supply a forwarding address. :-D


MrSuccess [ smiling an even bigger S E G :-D ...... than you know who .... ] :lol:
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Re: Ashton Embry about the misconducts of some teams

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Whatever the size of the alteration, A, the difference that makes to flow rate of blood is in proportion to (A times A times A times A). Four dimensions: length, width, depth, and time. It is hugely more important, to a major blood vessel, than a linear percentage. Drs. Zamboni and Sclafani, and many others, use CSA. At least cross-sectional area has 2 of those dimensions!
It is for exactly this reason that any deposits on artery walls, under much higher pressure, are a very serious problem, typically called heart disease. But of course there is no problem when something gets in the way of vein flow. Jugulars and azygus veins don't cause as fast and dramatic a death...
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Re: Ashton Embry about the misconducts of some teams

Post by frodo »

Sorry about the wrong attribution. I found the Joan article through the Direct-MS web page and I thought it was from Embry.
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Re: Ashton Embry about the misconducts of some teams

Post by cheerleader »

frodo wrote:Sorry about the wrong attribution. I found the Joan article through the Direct-MS web page and I thought it was from Embry.
no worries, Frodo...glad the note is getting around, and that Dr. Embry linked it on his site. Just saw it was retweeted by an medical ethics board in France. Really hope people ask how UBC could make up a whole new way to measure stenosis and then publish a paper using this fallacious method.
cheer
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dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
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Re: Ashton Embry about the misconducts of some teams

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Joan is all over the world......without leaving home :mrgreen:
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Re: Ashton Embry about the misconducts of some teams

Post by MrSuccess »

is there a more detailed report ? Can someone illustrate the "new " method of measuring the narrowings ?

For example .... how much MORE than 50% blockage? 51 % ? 81% ? Male v Female ?

Does the narrowing get better or worse , the longer the MS course ? Dr. S ?


MrSuccess suspects treating [ ballooning ] CCSVI is vital , as soon as the first symptoms
start to show up .

Did Dr. Traboulsee use IVUS ? Did he treat - expand - any narrowings ?

It clearly looks like a " quickie " medical investigation , to MrSuccess. :twisted:



MrSuccess " when I walk in a room ...... no one knows who I am ...... "
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