A recent debate surrounding the pathogenesis of multiple sclerosis is analysed in terms of the skills, interests and backgrounds of the medical personnel involved. It is noted that the proponents of the vascular theory possess developed expertises in interpreting disease in structural, vascular terms, whereas their opponents' skills lie in immunology or neurology. Different observers have produced different conceptions of the disease because modes of observation, and the points from which observation takes place, differ. It is also noted that the debate over the causation and treatment of MS has occurred between a large and powerful social group and a weak and marginal one. The effects of this power inequality on the production and assessment of knowledge about MS are investigated.
Adhesion molecules and white cells activation
T cell migration-infiltration
Local iron overload
Urine haemosiderin test
Fibrin cuff (on going reparative process)
mrhodes40 wrote:Zap the second paper ought to be required reading; it is that good a paper. it details the concept of cognitive dissonance well and it also mentions a "social" angle to the bias an individual doctor / medical commuinty has, namely that if you are a neuro, you assess everything in terms of YOUR model and nothing else is given a fair hearing because your training, understandings and beliefs are so well accepted by you as the only way that you CAN'T hear any other ideas. The article points out the aspect of power for the neuro community and their supposed "right" to veto any other models or ideas even though they have little background to assess it fairly and a social drive to reject it even if they did understand it. I really liked the article.
"there's no lifelong profit model"
I liked it too, but there should be another paper out there somewhere that digs more into the bias introduced by the role of the pharma companies
At the same time, the functional or morphologic
incompetence or absence of either the IJV valves or
the vertebral venous valves may be the cause of cough
headache, cerebral morbidity after positive end-expiratory
pressure ventilation, and some types of cerebrovascular
but if Dr. Zamboni has found stenosis and blockage in every MS patient he's tested, the surgical removal and stenting looks like only viable option. As Marie mentioned, Dr. Zamboni is currently stenting 100 MS patients....he must be pretty confident to be performing an invasive procedure.
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