You guys may never know how thankful some of us who almost get it but don't have the time to research all the details are.
mrhodes40 wrote:I was thinking about the blockages earlier today and it occured to me that they are not 100% so perhaps that is why it we get by ....maybe losing only 50% of the lumen is manageable for the body, but beyond that it starts to get ahead of the body's ability to compensate.
Then these other things are a bigger deal than they would be like NO issues or vasocontrictive things, fats in the diet ball up there a little bit etc. Thus it may be true that it is an issue of degree and intermittant lifestyle issues may make the difference.
Complete occlusion. What we call progressive MS. If it strikes the jugs, you have SPMS. If it strikes the azygos, you have PPMS.
This is all just rambling and surmising...but I really think this model makes more sense than anything else I've come across.
chrishasms wrote: I continued to spiral downhill fast because I think I smoked cigarettes too.
Analyzing over 2,000 medical records in the General Practice Research Database (GPRD), researchers identified 179 British patients who were originally diagnosed with relapsing-remitting MS, a form of the disease in which symptoms fade and recur in unpredictable patterns. Patients who were current or past smokers were 3.6 times as likely as patients who had never smoked to develop secondary progressive MS, a later stage of the disease marked by steady deterioration of the central nervous system. This disease progression also occurred more quickly in patients who were identified as current or past smokers. The study also supported earlier research showing that smoking may increase the risk of initial MS diagnosis. Current and past smokers were 30% more likely to be diagnosed with MS than those who had never smoked.
During labor and delivery activation of coagulation occurs with consumption of platelets, coagulation factors and inhibitors. Obstetric complications during delivery can excessively activate the coagulation system and disseminated intravascular coagulation may ensue. Current treatment for postpartum coagulopathy is non-specific and primarily consists of replacing blood components. If specific causes or markers of abnormal coagulation can be identified in women at risk, then it might be possible to target (with specific medications) specific abnormalities early in the process and decrease hemorrhage and the need for blood transfusions.
the irony is, medical researchers could never explain why smoking was so bad for MS.....what does a cigarette have to do with autoimmunity? They said it showed "risky behavior" and smokers were more promiscuous and had more viral exposure (EBV, HPV) WTF????
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