Guitar guy, you are right, Lesions appear and disappear all the time.
HERE IS A SERIAL MRI PICTURE
Note how in August a lesion appears and it disappears the next month. Note how in April one appeared that was also gone the next month. There is nothing miraculous or unusual about that.
I have seen several of these serial MRI's on MS patients on the net and they all show exactly the same thing: lesions appearing and disappearing. My neuro even told me black holes can disappear.
My own MRI's are like Sharon's. NO inflammation. Rejected by JH a year ago. And I expect no changes in my 18 year old lesions. Believe it or not, I have the same 4 lesions I did at the beginning. THEY ARE SCARS. Not inflammation or simple demyelination that can heal and look different on MRI. They are not going to. I actually have a 5 year old back hole too. If they do look different next month I'll be so shocked they'll have to pick me up off the floor from a dead faint.
Inflammation comes and goes. It has little clinical significance other than to the extent that the inflammation itself is causing the damage of MS...and that is a question that is open for debate. If you are a AI theorist you have been claiming it s all about the inflammation being the scause of MS lesions.
If you are not AI but rather think MS is another physical process, possibly CCSVI, inflammation is just a normal physical response to the damage and it is nothing more than evidence that the damage is still on going.