Here's a study of a man involved in a bad auto accident. He had massive blood loss, and his brain was deprived of oxygen for a while. He develops demyelinated lesions in his brain and has an overactive bladder.
Unlike previous reports of hypoxic-ischemic demyelination, our patient lacked any cortical abnormalities, presumably due to isolated white matter changes. This report alerts physicians to the possibility of hypoxic-ischemic demyelination due to global hypoxia-ischemia as an etiologic factor for neurogenic bladder.
http://www3.interscience.wiley.com/jour ... 9/abstract
Here's a man who suffered from hypoxia due to carbon monoxide poisoning.
A 40-year-old male presented with acutely oncoming neuropsychiatric symptoms in the form of extrapyramidal disturbances, personality change, behavior changes and urinary incontinence. One month prior to this symptomatology, he had been found unconscious in his closed room where a coal fire was burning overnight. He recovered completely in two days with supportive therapy. Magnetic resonance imaging during this presentation showed bilateral white matter changes suggestive of demyelination.
Both of these men recover, once the hypoxic incident is over, the brain gets oxygen again, and the lesions eventually heal.
If MS is a chronic, ongoing hypoxic insult to the brain and spine, due to CCSVI...it could be exacerbated by any event when further lessens oxygen to the brain...high altitude, viral or bacterial infection, vasoconstriction. More lesions are formed, the damage continues.
The hypoxia created by CCSVI is chronic, ongoing, but much slower than what happened in the studies above. It takes many years to develop damage. Restore oxygen to the brain and spine, and healing and remyelination should take place.