Needled wrote:Thanks NHE. I got the gist of it all. Now I need to know how much, how often, and if there are extracts, what are the best ones? I bet I know someone who could help. Oh, Jimmylegs, are you around? I think we need you over here for a lesson on green tea...
Hemosiderin or haemosiderin is an iron-storage complex (ferritin being the other). It is always found within cells (as opposed to circulating in blood) and appears to be a complex of ferritin, denatured ferritin and other material. The iron within deposits of hemosiderin is very poorly available to supply iron when needed.
Several disease processes result in deposition of larger amounts of hemosiderin in tissues; although these deposits often cause no symptoms, they can lead to organ damage.
Hemosiderin is most commonly found in macrophages and is especially abundant in situations following hemorrhage, suggesting that its formation may be related to phagocytosis of red blood cells and hemoglobin. Hemosiderin can accumulate in different organs in various diseases.
Iron is required by many of the chemical reactions (i.e. oxidation-reduction reactions) in the body but is toxic when not properly contained. Thus, many methods of iron storage have developed.
mrhodes40 wrote:Since hemosiderin is a form of iron seen when blood has gone where it does not belong and the immune system had to clean it up, that is a good support of what we are talking about with CCSVI.
In fact, it (CCSVI) is a logical explanation as to why the entire brain is affected in MS, why the disease tracks backward along the venous drainage system, and why it emanates from the white matter near the ventricles in the drainage of territory of the medullary veins. If the thalamostriate system is affected with increased iron content along the venous system as I believe it is, then this all falls into place. CCSVI may just be the etiological source we have all been looking for. If so it provides great hope for MS patients worldwide and we cannot and should not wait years for funding to allow us to demonstrate this point.
LR1234 wrote:What I can't work out is if we should lower our iron intake or should we increase it? The only reason I say this is because weirdly I seem to feel better when I increase my iron levels and increase vitamin C (maybe it encourages the body to metabolise it better or something)
The Swank diet suggests lower iron intake would be better as it excludes red meat.
If not don't mess about with adding it or denying it. Iron overload can be a problem, and anemia can be a problem. Iron is not like, say, a b-vitimain that just goes out in the urine if you get too much. It accumulates.
It was found that iron levels were significantly higher in people with MS, particularly so in those with the secondary progressive form of the disease.
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