1eye wrote:What evidence is there for saying the majority of "MS" patients have low iron?
I've gathered that from my readings over the years. I study iron metabolism and MS.
To make things clearer, this would be as shown on an iron test result from blood levels. That does not mean that iron is not in tissues or free iron. See http://www.hindawi.com/journals/msi/2011/606807/
as an example
Iron and Neurodegeneration in Multiple Sclerosis
Michael Khalil,1,2 Charlotte Teunissen,2 and Christian Langkammer1
1Department of Neurology, Medical University of Graz, A-8036 Graz, Austria
2NUBIN, Department of Clinical Chemistry, VU University Medical Center, 1007MB Amsterdam, The Netherlands
Across the general population the majority of women have low iron levels, so to me that state is normal, MS or not. MS predominantly affects women.
I have heard of a few people on this forum having regular phlebotomy because it make their "MS" feel better. If anything, that would come from the initial condition being an overload of iron.
Yeah, I know, I'm still having one pint taken four times a year. Works great for me.
I have high iron levels as does my sister with MS. But from my readings, we are not the average.
Anyway, that's my take on it, and if you think the hemosiderin deposition gets there simply from old blood, that's your take. I think it's more about iron transport and metabolism No doubt they'll get to the bottom of it eventually. I really doubt that one shoe is going to fit all.
Mark - Not sure what you want me to comment on.