thanks for taking the time to fill us in. I'm just so happy for you and Mel...really ecstatic. It's all well-deserved, and we celebrate with you both.
Glad Dr. Dake and Dr. Zamboni are going to apply for that grant together...between the two of them, there's a winning combination of endovascular expertise and flow knowledge. I love it when the docs work together! I also agree that a blind trial seems difficult, if not impossible...and kind of cruel (to undergo the venous catheter without treating? Yikes!) I think a study combining SWI-MRi and oligoclonal banding in CSF before/after will provide the "proof" everyone wants.
The Mel and Jeff types are the most affected early by stenting...because they had the least amount of brain tissue damage...(worth noting that both Jeff and Mel had 20 lesions each, yet hardly any disability-it's not about the lesions, people!) BUT I know Zamboni's team has seen healing in those further along. Jeff's our oldest stento-teer at 4 months. That's nothing in MS time. Zamboni's team saw changes after 18 months in the more progressive patients.
The accessory nerve pain is going to be an issue. It's been bad for the folks with high stents in C1-3, because that's where the accessory nerve travels across the IJV. If the area is tight enough to constrict a vein, opening the vein takes away space from other residents. Jeff had bad pain for a month or so, but others like Marie and Lew have had more serious issues. Dealing with this will have to become part of the protocol. We all owe Marie, Lew and those with complications our heartfelt thanks. The doctors will learn from their bravery.
wow...it's only been since April when we first met Dr. Dake. Imagine where this may be in another 6 months.
...whatever technique Lew shared with you...glad it worked