M 47 Yrs.
Lesion locations (most affected side, if known), number:
Prednisolone, Mitoxantrone (3 injections), Methotrexate since 09/2004, LDN since 02/2008.
Vit.D3 started 2010/01/07 0.5g/2 days
Catheterized bladder for 18 months, been solved after LDN intake.
Surgery for cataracts due to steroids (Prednisolone) in 09/2007.
MS symptoms before stenosis intervention:
Paralyzed waist down, right arm/hand barely moving; last limb already weakened. Incontinence, Moments of "black conscious state" (<10secs), difficulties swallowing; constantly need help (wake-up, clean, change diapers, clothing....). Spasms, stifness, clonus of the left hand (remaining functional limb).
*(Huge improvement by the use of external catheter - Only during the night I need a diaper - Cheaper and much more convenient - I recommend that.)
I hope to think I have no cognitive problem
MRI 2010 July 7th at Tai Da Hospital Taipei
MRI Study without and with enhancement showed:
1. No evidence abnormal DWI or SWI lesion.
2. Focal bright SI on T2WI, low on T1WI, with negative mass effect and no definite abnormal enhancement was shown in right medulla, bilateral cerebral peduncles, periventricular and subcortical white matter.
3. The ventricles and sulci were dilated diffusely and symmetrically.
4. The major vessels are unremarkable at the Willi's circle.
5. Atrophic cord shown with abnormal SI on T2WI at C4 to C7
6. Degenerative disc shown in the levels of whole C Spine with probably OPLL. The study wasn't for spine so the detail is not enough.
Impression: multiple old insults. Leukoaraiosis? Atrophic cord, chronic change? MS?
Number of relapses before intervention (if applicable):
EDSS before CCSVI: 8+
FSS before CCSVI intervention: N/R
MSIS before CCSVI intervention: 121 (?)
Are you using Inclined Bed Therapy I.B.T? Y/Not now
2009.12.27 => No signifying difference.
2010.01.07 => Blood pressure change? Cant verify.
2010.01.11 => Raised to full 16cm, no obvious changes.
2010.01.26 => No changes - But wife's feeling better
2010.02.05 => Legs and feet burning 'inside' during the day.
2010.02.26 => Legs/feet burning stop. Spasms and stiffness subsided.
2010.03.11 => Nothing to report; +ve or -ve.
2010.06.02 => No changes.
2010.06.07 => Lowered back to 0°, still nothing changed.
2010.07.12 => No more attempts; temporarily.
<<Will report when/if resume>>
Have you had a procedure for stenosis yet: Y
STENOSIS PROCEDURE HISTORY
Date/location of testing&procedure:
12.03.2009 National Taiwan University Hospital
No anomalies detected
But "standard protocol"
03.31.2010 National Taiwan University Hospital
MRx w/ Gadolinium (not sure what has been checked)
No stenosis reported in both jugulars. NTUH will not go further if no obvious stenosis found.
Second opinion seeking
07.02.2010 Veteran General Hospital Taiwan (VGH)
07.05.2010 Echo Doppler and intracranial (VGH)
07.12.2010 MRV with contrast (VGH)
Your Left jugular vein is compressed by the cervical spine at level of C 1. The lumen of Lt jugular vein is very small at the level of C1, >90% stenosis by MRV study. The jugular venous valves are functioning normal. Because there is no any stent designed for the vein, therefore Dr. XXXX, who is responsible for the intervention treatment, will find a suitable stent available on the market, though designed for the artery, for the special location of the vein. The detailed study of azygos vein needs conventional venogram, and MRV of azygos vein only can provide limited information.
Number of relapses since first CCSVI intervention:
Impact on your MS symptoms in words (include date in brackets if there have been multiple updates):
EDSS as of this update (self-assessed or physician-assessed?)
FSS as of this update:
MSIS as of this update: