Scorpion I do not blame you a bit! I do not. I've had MS for 18 years and like you have been dropped on my head numerous times--- We are justified to be skeptical, super skeptical, to be frank. After a while your heart just can't take it any more.
Please do ask good questions! I think there will be some real surprises as this develops personally. Will we all be on Campath and stents? heck there is not enough yet to know we will not need suppressive as well, we may.
BTW, I had a big advantage, my skepticism took the form of "MS is not likely autoimmune" some years ago, & I had very good reasons for believing that. When this came along for me it was the super exciting thing to dig in and study, the best thing to come along in ---well, ever.
But it was always a really good model. IF and this is a big qualifier, a person CAN read the related research and I mean like the mean transit time studies and the old vascualr studies, there is vastly more to support this than Zamboni which is why I was personally all in even though the Ferrara team is only one group and the "100%" is unusual. It was never about the technicalities of the current studies, it was always about the wider picture: it fits really, really well in a lot of ways. This made me happy to volunteer to be part of the work going forward and accept the risk of a new unproven idea.
It is going to be great fun for us all to watch this develop over the coming months...
and may I say, as an MS patient for 18 years, I still almost get tears in my eyes when I realize we really are talking about months... They are going to have to fast track this if stuff is really as conclusive as it appears it may be
Remember what it felt like when you first read of Tovaxin and realized it was going to be YEARS............