Exactly! People with two H282Y/H282Y or H282Y/H63D genes are being diagnosed much more easily now. They get their iron lowered under medical supervision by phlebotomy and many get their vitality back. The doctors seem to write off anyone with only one gene as "unlikely" to overload. My doctor (ex now
) did that. Point is, there are many more genes yet undiscovered, I think there are presently 38 others that create variables in iron metabolism. We only get tested for the two main ones. So if you only show up with one, say H282Y the other gene is still wild (?) and could be an influence.
The parameters for diagnosis with iron overloading are too high.
I started to get my brain symptoms of MS and Epilepsy with ferritin of just 175 (dx for overload usually >200 for menstruating women), tranferin saturation of 62% (Dx over >45%). I was still getting fatigue/sleeping/arthritis symptoms at ferritin of 135 and Tsat of 51%.
I must be a bit lower than that now, since the blood donation.
I'm not looking forward to going to the Haemotologist. I have to hope he has enough vision to connect the brain symptoms with the iron overload, and of course the miraculous cure I'm experiencing, long may it last!
100mls taken at blood tests gave me 4-5 days of energy & normality.
When it ended I slipped back into the sleeping/fatigue immediately.
470mls has given me 8 days of bliss so far.
It's kind of scarey that I may slip back into that abyss again shortly.
I can't give blood again till April.