Multiple Sclerosis Society UK 'Experts' question CCSVI vein disorder-MS theory
British medical 'experts' from the MS Society are questioning a new theory put forward by Italian vascular surgeon Dr. Paolo Zamboni that multiple sclerosis (MS) was caused by blocked veins in the neck or chest.
Dr. Zamboni’s theory centres around the repeated references in research text books to deposits of iron in the blood vessels and a link to MS.
Excess deposits of the heavy metal have been proven to lead to inflammation and cell death in the laboratory. These are both characteristics of MS.
Using ultrasound to examine the vessels leading in and out of the brain, he said he had tested his theory in people and found that in a majority, including his spouse who he also experimented upon, the veins draining blood from the brain were malformed or blocked. In people without MS, they were not.
He further suggested that iron was damaging the blood vessels and allowing the heavy metal, along with other unwelcome cells, to cross the crucial brain-blood barrier, a process termed Chronic Cerebrospinal Venous Insufficiency (CCSVI).
He said he had devised an experimental procedure that involved removing the blockage in the veins that carry blood to and from the brain.
So far, he has performed the angioplasty-like surgery, known as "la liberation" in Italian, on 120 MS patients, including his wife, whose multiple sclerosis provoked his interest in tackling the disease.
His findings were published in the Journal of Vascular Surgery and scientists at the University of Buffalo in New York announced they would test his theory by recruiting for a large study.
However, British "experts" sound skeptical. Research Communications Officer at the MS Society, Dr Susan Kohlhaas, said: "Several medical advisers to the MS Society have read through the papers published by Dr Zamboni, and have heard him lecture on the subject.
"They are not convinced by the evidence that blockages to draining veins from the brain are specific to people with MS, or that this explains the cause of MS at any stage of the condition........................"
More - http://www.msrc.co.uk/index.cfm?fuseact ... ageid=2944