Here's the deal....neurologists recently have more diagnostic equipment available to them. We were discussing the research linking TGA to jugular scans last year. I don't think TGA or CCSVI are mutually exclusive. TGA looks like a one time whollop to the CNS, while CCSVI is an ongoing problem that creates venous congestion.
Transiant global amnesia happens after stressful situations-
Quote:
In many cases, an episode of transient global amnesia can be traced to a physically or emotionally stressful incident shortly before symptoms began. Among the triggering events commonly reported are:
Sudden immersion in cold or hot water
Strenuous physical activity
Sexual intercourse
Medical procedures, such as angiography or endoscopy
Acute emotional distress, as might be provoked by bad news, conflict or overwork
The underlying cause of transient global amnesia is unknown. There appears to be a link between transient global amnesia and a history of migraines, though the underlying factors that contribute to both conditions aren't fully understood.
from the Mayo Clinic page on TGA
A sudden, hyperacute ischemic change is very different than an ongoing problem. I reiterate, CCSVI and TGA may not be mutually exclusive. Tiny lesions are detected in some patients after TGA-
Quote:
Hakan et al demonstrated tiny increases in signal in the left parahippocampal gyrus and splenium of the corpus callosum on DWI in one patient. This method of imaging allows detection of hyperacute ischemic change. Liang et al and Yang et al have also recently used DWI to document tiny lesions in the hippocampus of patients with acute TGA.1,2 However, Eustache et al reported a PET study consistent with a spreading depression in the left lateral frontal cortex. This case also featured oligemia in the left occipital cortex.3 Strupp et al found mainly medial temporal changes on DWI in 7 of 10 patients with TGA. They suggested that cellular edema or spreading depression could be responsible, not just ischemia.4
http://emedicine.medscape.com/article/1160964-overview
The studies are ongoing. It appears there is substantial evidence that jugular valve malfunctions may play a part in TGA. But that does not nullify CCSVI studies. I think the Germans are wrong to discount CCSVI without researching it.
We have to be really careful about making comments regarding well-established, peer-reviewed research on here, just because it doesn't seem to fit our particular paradigm. We don't know enough about how TGA and CCSVI are different or how they are the same YET, but research will continue to help us understand.
Here is the Chung research I put on the big CCSVI forum last year, Marie has it linked in the research sticky. There is still more to learn regarding jugular venous reflux. Please read this paper-
http://health.elsevier.com/ajws_archive ... 3A4703.pdf
cheer
_________________
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
dual stents placed 5/09
CCSVI in MS 
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