Does High Dose D increase creatinine?

A forum to discuss the Coimbra Protocol which uses high-dose vitamin D3 to treat multiple sclerosis.

Does High Dose D increase creatinine?

Postby mrtmeo » Tue Mar 14, 2017 10:12 am

I was looking at vilnietis doc on his levels and noticed his creainine went up from 72 before treatment to 86 mmol/l but 17 months, later came back down to 78.
Also, research has indicated the D is renal protective.
https://www.ncbi.nlm.nih.gov/pubmed/22160397

Just wondering if anyone knows if D increases creatinine at high doses.
Mother was on Rituximab and prednisone for Microscopic Polyangiitis which attacked the kidneys and lungs.
Drs denied her dialysis and appropriate treatment for her MPA and forced her into hospice.
She is in heaven and free from pain.
mrtmeo
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Re: Does High Dose D increase creatinine?

Postby AntonioBR » Tue Mar 14, 2017 8:48 pm

Well, it depends on each person.

But generally, it does not change. At least I never saw people complaining about their creatinine levels.

As you already know my brother takes huge doses (250,000 iu's) and some of his creatinine levels were:

10/21/14: 1 mg/dl
24/10/14: 0.9 mg/dl
08/10/15: 1.2 mg/dl
08/19/15: 1.1 mg/dl
02/27/16: 1 mg/dl
09/06/16: 1.10 mg/dl

Reference values:
Men.: 0.66 to 1.25 mg/dl
Women: 0.52 to 1.04 mg/dl

I do not have their 2017 exams on my laptop. But I know that it did not change because he would tell me.
Last edited by AntonioBR on Fri Mar 17, 2017 6:50 pm, edited 2 times in total.
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Re: Does High Dose D increase creatinine?

Postby mrtmeo » Wed Mar 15, 2017 2:25 pm

Thanks for the example.
It does look like some fluctuation happens.
Do you know if there is a maximum calcium intake allowed by the protocol?
I know that calcium will make the PTH come down and could cause a false calculation on the D requirements.
Mother was on Rituximab and prednisone for Microscopic Polyangiitis which attacked the kidneys and lungs.
Drs denied her dialysis and appropriate treatment for her MPA and forced her into hospice.
She is in heaven and free from pain.
mrtmeo
Family Elder
 
Posts: 117
Joined: Sun Aug 28, 2016 4:44 pm
Location: Wisconsin, USA

Re: Does High Dose D increase creatinine?

Postby AntonioBR » Wed Mar 15, 2017 9:51 pm

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The fluctuations seem very small.

When he was taking 180,000iu's (08/10/15 - 1.2 mg/dl) creatinine was higher than when he started to take 250,000iu's (02/27/16: 1 mg/dl)


Do you know if there is a maximum calcium intake allowed by the protocol?


No, there is not an exact upper limit of calcium intake. Because every patient is different and each one takes a different dose of vitamin D.

First, the patients need to reduce their calcium intake and follow a low-calcium diet.

Then after 2 or 3 months (for patients without kidneys problem) doctors check patient's exams and do an adjustment if necessary.

It works analogously as the vitamin D dose adjustments.
AntonioBR
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Posts: 486
Joined: Sat Dec 12, 2015 11:06 am


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