Weight Gain

A board to discuss the Multiple Sclerosis modifying drug Copaxone

Weight Gain

Postby Ravenmccy » Fri Nov 18, 2011 4:24 pm

I was diagnosed with MS in February of this year. Since then I have started copaxone in early March. By June put almost 5-6 pounds. and now I am up a good 10-15. I have tried weight watchers and I am now on south beach but i just keep putting it on. I know a lot of this is likely comfort eating, but I shouldn't still be gaining while on such a severe diet like south beach. Any thoughts? How would copaxone cause any weight gain?
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Re: Weight Gain

Postby lyndacarol » Fri Nov 18, 2011 6:42 pm

Since you asked for "any thoughts," here are mine – uniquely mine and not generally shared by anyone I have found to date.

Insulin is necessary for the human body to put on weight/fat. I suspect that your pancreas is secreting more insulin than necessary, and consequently your body is storing every bit of glucose in the bloodstream as additional weight/fat. Drastically cutting out carbohydrates may help. I can think of no reason why Copaxone would cause a weight gain.

My suggestion is always: request your physician to order a "fasting serum insulin test."
My hypothesis: excess insulin (hyperinsulinemia) plays a major role in MS, as developed in my initial post: http://www.thisisms.com/forum/general-discussion-f1/topic1878.html "Insulin – Could This Be the Key?"
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Re: Weight Gain

Postby Ravenmccy » Sat Nov 19, 2011 8:29 am

Very interesting comments. I thank you and will certainly get a test soon. Although, if this were the case a diet like South Beach should certainly be affective. Low carb, fat, and sugar - its was originally designed for diabetic patients, yet I continue to gain weight on it. What sort of methods are there for reducing insulin production?
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Re: Weight Gain

Postby lyndacarol » Sat Nov 19, 2011 4:52 pm

At the moment diet is the only way to reduce insulin production; there is no medication approved for reducing insulin, unless the malfunctioning of the pancreas is the result of infection; then, antibiotics may help.

I agree that a no carb diet, such as South Beach, should be effective. In my own situation, I find that I am EXTREMELY sensitive to any carbohydrates, even to sugar alcohols such as sorbitol (which I have found in toothpaste, mouthwash, even my fish oil capsule), xylitol (which I know is in some chewing gum), and others. Even mucus naturally produced in the body (I have had chronic sinus drainage since first grade.) contains a heavily glycosylated component.

Although Dr. Terry Wahls is focusing on mitochondria, I think her success with diet is largely due inadvertently to reducing insulin production. Check out her website, http://www.TerryWahls.org Her story is truly remarkable!
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Re: Weight Gain

Postby lyndacarol » Sun Nov 20, 2011 12:01 pm

Ravenmccy – if you do request an insulin test, you may be interested in reading Dr. Mercola's opinion of results; he thinks 3 UU/ML or lower is desirable (My lab reports 6-27 as "normal." My first test resulted in 12 UU/ML; no later test was less than 9.)

http://www.mercola.com/nutritionplan/index2.htm


Factor # 1 : Your Insulin Level
Insulin is absolutely essential to staying alive, but the sad fact is that most of you reading this have too much floating around, and it is pushing you towards chronic degenerative illness and increasing the rate at which you age.
Most adults have about one gallon of blood in their bodies and are quite surprised to learn that in that gallon, there is only one teaspoon of sugar! You only need one teaspoon of sugar at all times -- if that. If your blood sugar level were to rise to one tablespoon of sugar you would quickly go into a hyperglycemic coma and die.
You body works very hard to prevent this by producing insulin to keep your blood sugar at the appropriate level. Any meal or snack high in grain and sugar carbohydrates typically generates a rapid rise in blood glucose. To compensate for this your pancreas secretes insulin into your bloodstream, which lowers your blood sugar to keep you from dying.
However, if you consume a diet consistently high in sugar and grains, over time your body becomes "sensitized" to insulin and requires more and more of it to get the job done. Eventually, you become insulin resistant, and then diabetic.
If you have high cholesterol, high blood pressure, type 2 diabetes, or are overweight, it is highly likely that you are eating too many grains -- yes, even unrefined whole grains -- as this is the most common culprit causing your insulin level to become abnormal.
Compounding the problem, when your insulin levels rise due to an excess of carbohydrates, they send your body a hormonal message telling it to store fat while holding on to the fat that is already there. So not only will excess carbohydrates make you overweight, they will effectively hamper your weight loss efforts too.
Your Fasting Blood Insulin TestTo find out your insulin levels, you need to get tested by your doctor. The test you need to ask for is a fasting blood insulin test, the test is done by just about every commercial laboratory and is relatively inexpensive. Facts about Your Fasting Insulin Test:
• This test is profoundly useful. It's one of the least expensive tests in traditional medicine, yet it is one of the most powerful. A normal fasting blood insulin level is below 5, but ideally you'll want to be below 3.
• You can safely ignore the reference ranges from the lab as they are based on "normals" of a population that has highly-disturbed insulin levels.
• This is a great test to do BEFORE you start your program as you can use it to assess how well you are progressing in the program.
• If your level is above 5 you will want to consider significantly reducing most sugars and grains, even whole wheat grains, until you lower your level. Once you've normalized your insulin level you can reintroduce grains into your diet at a lower level to optimize your health.
Exercise is of enormous benefit in improving the sensitivity of your insulin receptors, and help normalize your insulin level far more quickly.
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