Thighs are my nemesis. They seem so fat to me yet they don't have enough fleshiness for the shot. i go shallow, yet i can have swollen ITCHY sites for up to 3 days. I found the reaction to be way less when I reserve my thighs for days I know I won't be doing alot of walking. I think the fabric rub intensifies the rx.
back of my arms can get a bit reactive as well, but all in all I gladly take these rxs. rather than the interferons.