Japanese Rice may help MS

A board to discuss various diet-centered approaches to treating or controlling Multiple Sclerosis, e.g., the Swank Diet

Japanese Rice may help MS

Postby Tyr616 » Wed Dec 22, 2010 10:16 pm

The purpose of the present study was to develop a peptide fortreatment of multiple sclerosis (MS). We have tested the effectof a novel antiinflammatory peptide (KGHYAERVG, termed IIIM1)on experimental autoimmune encephalitis (EAE), an animal modelof MS. Our findings demonstrate significant reduction in neurologicalscore following oral administration of IIIM1, as compared tothe control groups received the vehicle (saline). Structuralstudies revealed that the entire peptide is required for activity.The peptide caused significant reduction in IL17, interferongamma and IL12 production by isolated splenocytes and concomitantelevation of antiinflammatory cytokines. IIIM1 elevated T regulatorycells (Tregs, CD4+CD25+FoxP3+) in brain and spleen of EAE mice.Similar proliferative effect was observed in isolated humanand mouse Tregs in vitro. Stimulation of Tregs by IIIM1 causedproduction of a new peptide termed RA1 present in Oryza SativaJaponica group. This Japanese rice peptide ameliorated neurologicalsymptoms in the EAE model. Similar beneficial effect was observedupon oral administration of an extract of Japanese rice. Inconclusion, oral treatment with IIIM1 ameliorates EAE symptomsvia stimulation of Tregs to proliferate and produce RA1 whichreduces EAE symptoms. These findings may explain the relativelylow prevalence of MS in Japan and other Japanese rice-eatingpopulations. (This work was supported in part by The IsraelScience Foundation grant 747/05).


http://www.jimmunol.org/cgi/content/mee ... racts/96.1
User avatar
Tyr616
Family Member
 
Posts: 37
Joined: Sat Feb 27, 2010 4:00 pm

Postby CuriousRobot » Mon Jan 03, 2011 7:46 pm

Sweet deal.
User avatar
CuriousRobot
Family Elder
 
Posts: 173
Joined: Tue Nov 02, 2010 4:00 pm

Postby Tyr616 » Mon Jan 03, 2011 8:03 pm

Another interesting thing I read is that rice bran contains something called IP6 which may chelate and remove Iron from the body. But apparently white rice doesn't containt IP6, so I'm confused what hte reasoning behind white rice helping MS is. But that study apparently says it does. But, IP6 might be a supplement worth looking into for the possibility it helps remove excess Iron.
User avatar
Tyr616
Family Member
 
Posts: 37
Joined: Sat Feb 27, 2010 4:00 pm

Postby gainsbourg » Tue Jan 04, 2011 3:56 am

As I read through the article I was thinking the same thing about IP6. It reminded me how the Tsuno Foods & Rice Company in Japan started this whole thing about the healing benefits of rice bran a few years back.
User avatar
gainsbourg
Family Elder
 
Posts: 218
Joined: Sat Sep 06, 2008 3:00 pm
Location: London


Return to Diet

Who is online

Users browsing this forum: No registered users


Contact us | Terms of Service