Once during an exacerbation, I was on 1200 mg per day for 3 days. The idea then is to taper off slowly. I went to 80 mg for 3 days, per doc instructions, and felt like I was going to die. I thought it was the predizone and stopped. That was a mistake. He put me back on 80, 60, 40, 20 mg for 3 days each and survived, but just barely. My family, not so much. I screamed a lot and then had diarrhea for 4 months. I've never taken it again but would if an attack was bad. It totally cured my symptoms at that point - my whole left side was paralyzed and it came back. I hope others respond.