Necrostatin is a lot like N-Acetyl Cysteine, but it is a drug that is being developed.
Interesting for those who like low fat diets and antioxidants.
"Increased production of free arachidonic acid occurs during brain ischemia and inflammation as a result of activation of phospholipases . Arachidonic acid is a substrate for cycloxy-genases and lipoxygenases (LOX). Metabolism of arachidonic acid through these two enzyme systems is a potential source for free radicals and peroxides and thus oxidative damage. Altered arachidonic acid metabolism has been implicated in cerebral ischemic injury, neurode-generative diseases and psychiatric disorders ."
And some really good information in regard to autoimmune diseases and dietary supplements:
Necrostatins at a glance
• Discovered by Harvard researchers
• Can inhibit programmed cell death
• Vast range of potential applications — cardiovascular, neurological, organ failure and more
• Licensed by TetraLogic, which will file FDA application in 2010
• Several animal trials now under way in Boston area
• Human trials slated for next year(2011)
http://www.masshightech.com/stories/200 ... friendform